Results 181 to 190 of about 12,206 (307)

Stage I Seminoma of the Testis [PDF]

open access: yes, 1991
Allhoff, E. P.   +4 more
core   +1 more source

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

open access: yesCancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda   +7 more
wiley   +1 more source

Agrimoniin Alleviates Ferroptosis in Cold‐Stored DCD Liver Grafts Through Activation of the Nrf‐2 Pathway

open access: yesCell Proliferation, EarlyView.
Supplementing the liver preservation solution with agrimoniin protects donation after cardiac death (DCD) grafts by activating the Nrf‐2 pathway. This reduces ferroptosis, oxidative stress, and inflammation during cold storage, significantly improving graft viability.
Enqiang Chang   +5 more
wiley   +1 more source

The clinical value of nanocarbon suspension and methylene blue in sentinel lymphatic tracing and pathologic fine sorting of penile cancer: a multicentre prospective study. [PDF]

open access: yesAnn Med
Liu C   +22 more
europepmc   +1 more source

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

open access: yesThe FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni   +7 more
wiley   +1 more source

The Effect of Venous Incompetence and Arterial Insufficiency on Erectile Function [PDF]

open access: yes, 1990
Aboseif, Sherif R.   +7 more
core  

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

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