Results 181 to 190 of about 333,148 (322)

Progressive T cell exhaustion and predominance of aging tissue associated macrophages with advancing disease stage in penile squamous cell carcinoma. [PDF]

Sci Rep
Miyagi H, Yu X, Peak T, Dhillon J, Le C, Wang X, Yoder S, Marchion D, Lu X, Pettaway C, Moran Segura C, Zhang C, Roman Souza G, Yu A, Zemp L, Spiess P, Chahoud J.   +16 more
europepmc   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, EarlyView.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

Risk factors for postoperative surgical complications after inguinal lymph node dissection in penile cancer patients. [PDF]

Sci Rep
Gao Y, Shao Y, Hu X, Meng L, Li X.
europepmc   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

British Journal of Pharmacology, EarlyView.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange, Tobias Brunn, Charlotte Vetter, Konstantin Bloch, Nora Vedder, Chiel van Geffen, Philipp Gercke, Saeed Kolahian   +7 more
wiley   +1 more source

Is body mass index a risk factor for lymphnode metastasis in penile cancer? [PDF]

BMC Cancer
Machado RD, Faria EF, Júnior AAR, Stirpari F, Feres RN, Spiess PE, Shariat SF, Reis LO, Dos Reis RB.   +8 more
europepmc   +1 more source

Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi

British Journal of Pharmacology, EarlyView.
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia, Belén Climent, Bianca Barreira, Daniel Morales‐Cano, Ana Sánchez, Argentina Fernández, Borja García‐Gómez, Javier Romero‐Otero, Claudia Rodríguez, Laura Moreno, Dolores Prieto, María Jesús Larriba, Angel Cogolludo, Javier Angulo, Francisco Perez‐Vizcaino   +14 more
wiley   +1 more source

An Unusual Presentation of Gastric Cancer Metastatic to the Penile Shaft and Perineum. [PDF]

Cureus
Murray MG, Masi A, Kubinak NA, Stead LA, Eanelli TR.   +4 more
europepmc   +1 more source

A Multicenter Phase II Trial of Nimustine Hydrochloride Administered via Convection‐Enhanced Delivery in Children With DIPG

Cancer Science, EarlyView.
The efficacy of the CED of nimustine hydrochloride in pediatric DIPG was evaluated. One‐year survival rate from the start of radiotherapy was 60%. The treatment strategy demonstrated potential efficacy. ABSTRACT Diffuse intrinsic pontine glioma (DIPG) is a very challenging‐to‐treat pediatric malignant tumor, with a median survival time of < 12 months ...
Ryuta Saito, Masayuki Kanamori, Yoshiki Arakawa, Yohei Mineharu, Yasuo Aihara, Kentaro Chiba, Toshihiro Kumabe, Ichiyo Shibahara, Yukihiko Sonoda, Kenichiro Matsuda, Manabu Kinoshita, Aya Sato, Fumiaki Takahashi, Teiji Tominaga   +13 more
wiley   +1 more source

Trends in Human Papillomavirus-Related Health Burden in Greece from 1996 to 2021 with a Focus on Cervical and Lip, Oral Cavity, and Pharyngeal Cancer. [PDF]

Pathogens
Tampakoudis G, Anastasiou OE.
europepmc   +1 more source

Ultrasound fundamentals and their clinical implications for interventional cytopathologists

Cytopathology, EarlyView.
Interventional cytopathologists need to know about ultrasound physics and instrumentation to produce an image that faithfully recreates the lesion discovered by the sonographer and diagnosed by the radiologist. A deep quantitative understanding of physics is not required.
David Lieu
wiley   +1 more source