Results 221 to 230 of about 349,677 (327)

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali   +9 more
wiley   +1 more source

Penile Cancer Profile in a Central European Context: Clinical Characteristics, Prognosis, and Outcomes-Insights from a Polish Tertiary Medical Center. [PDF]

open access: yesCancers (Basel)
Czajkowski M   +7 more
europepmc   +1 more source

Precision Targeting of Myeloid Cells via Peptide Dendrimer‐Lipid Nanocarriers: A Novel Platform for Potent Cancer Immunotherapies

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Precision targeting of the spleen and myeloid cells of the tumor microenvironment, with minimal hepatic delivery, is achieved using a modular peptide dendrimer‐lipid nanocarrier. Functional assays, transcriptomics, and rodent models validate this novel myeloid cell targeting nanocarrier as an efficacious immunotherapy, both as a cancer vaccine platform
Lawrence James Billing   +9 more
wiley   +1 more source

B lymphocytes and tertiary lymphoid structures have a prognostic impact on penile squamous cell carcinoma. [PDF]

open access: yesJ Pathol Clin Res
Zavillová N   +8 more
europepmc   +1 more source

Noninvasive Detection and Thermal Ablation Therapy of Endometriosis Using Silica‐Coated Gold Nanorods

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
AuNR@Si(F)‐PEG nanoparticles are developed as theranostic agents for the noninvasive detection and photothermal therapy of endometriosis. The particles are preferentially taken up by the endometriosis lesions under photoacoustic image‐guidance, and used as thermal ablation therapeutics to shrink the lesions.
Panangattukara Prabhakaran Praveen Kumar   +7 more
wiley   +1 more source

Defining and sparing sexual function-related organs at risk for rectal cancer radiotherapy. [PDF]

open access: yesActa Oncol
Kronborg CJS   +23 more
europepmc   +1 more source

Biomolecular Interaction, Molecular Docking, Antimicrobial, Antioxidant, Antitumor, Cell Cycle Analysis, and Annexin V/PI Assay Efficiency of Some Co (II), Cu (II), Mn (II), Ni (II), Pd (II), and Pt (II) Complexes With a Halogenated Bidentate Schiff Base

open access: yesApplied Organometallic Chemistry, Volume 39, Issue 12, December 2025.
The ligand and metal complexes have been characterized experimentally and theoretically. Molecular docking studies were performed. The binding affinity toward biomolecules was analyzed. The in vitro antimicrobial (bacteria and fungi) behavior was evaluated. Furthermore, radical scavenging and in vitro anticancer activity, apoptosis, and cell cycle were
Elena Pahonțu   +13 more
wiley   +1 more source

Talquetamab‐Related Dysgeusia in Multiple Myeloma Compared to BCMA‐Targeted Bispecifics and High‐Dose Melphalan

open access: yesCancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Dysgeusia is a side effect of the anti‐GPRC5DxCD3 bispecific antibody talquetamab (TAL), but other myeloma treatments, such as high‐dose melphalan (MEL) with autologous stem cell transplantation (ASCT), are also known to alter taste perception in patients with multiple myeloma (MM).
Anna Fleischer   +14 more
wiley   +1 more source

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