Results 81 to 90 of about 5,528 (259)

Câncer do pênis: estudo da sua patologia geográfica no Estado da Bahia, Brasil Cancer of the penis: a study in pathological geography in Bahia State, Brazil

open access: yesRevista de Saúde Pública, 1984
Foram estudados 811 pacientes com o diagnóstico histológico de câncer do pênis, procedentes do Estado da Bahia, Brasil, entre 1952 e 1983. Cinqüenta por cento dos pacientes tinham entre 46 e 61 anos de idade.
Aryon de Almeida Barbosa Júnior   +2 more
doaj   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

open access: yesChemistry – A European Journal, EarlyView.
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser   +8 more
wiley   +1 more source

Targeting Ubiquitin‐Specific Protease 7 with Novel 5‐Amino‐Pyrazole Inhibitors: Design, Synthesis, and Biological Evaluation

open access: yesChemMedChem, EarlyView.
Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Matteo Lusardi   +9 more
wiley   +1 more source

Targeted Delivery of Lidocaine in Breast Cancer Cells via Zeolitic Imidazolate Framework‐8 Nanoparticles

open access: yesChemPhysChem, EarlyView.
Drug repositioning of lidocaine from local anesthetic to theranostic agent for breast cancer cells is enhanced by its encapsulation inside ZIF‐8 metal–organic framework. The aim of this article is to use zeolitic imidazolate framework‐8 (ZIF‐8) metal–organic frameworks (MOFs) as drug delivery system for lidocaine, a local anesthetic with recently ...
Nicola di Nicola   +7 more
wiley   +1 more source

Biology and Management of Male‐Bodied Athletes in Elite Female Sports

open access: yesDrug Testing and Analysis, EarlyView.
Graphical representation of the relationships of transgender and XY DSDF as male‐bodied athletes along the binary dimensions of biological sex. ABSTRACT The physical advantages in elite power sports that allow men to surpass women are derived from the experience of male puberty.
David J. Handelsman, Stéphane Bermon
wiley   +1 more source

Metastasis to the Glans Penis: An Unusual Site of Rectal Cancer Recurrence

open access: yesActa Médica Portuguesa, 2015
Secondary malignancy of the penis is a rare clinical condition, often associated with disseminated genitourinary malignancies. The prognosis is poor and the treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy ...
Beatriz Nunes   +3 more
doaj   +1 more source

PENILE NEOPLASM: AN ATYPICAL PRESENTATION

open access: yesPakistan Journal of Medicine and Dentistry, 2019
Penile carcinoma, representing less than one percent of all cancers in males, is a condition where diagnosis is frequently delayed, therefore the disease and its treatment results in significant morbidity and mortality in patients. There is no known etiology; however HPV infections are detected in most cases of penile cancer, so possible correlation ...
Sobia Rafi   +3 more
openaire   +1 more source

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk   +5 more
wiley   +1 more source

Carcinoma de células escamosas de pene

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2015
El cáncer se ha convertido en un problema sanitario de primer orden a nivel mundial, a pesar de los grandes programas diagnósticos y terapéuticos alcanzados en los últimos años.
Leonor Hernández Piñero   +2 more
doaj  

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