Results 161 to 170 of about 14,249 (201)
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Infection Control & Hospital Epidemiology, 1991
With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has increased greatly. This review summarizes the pharmacology, clinical experience in the treatment ofPneumocystiscarinii pneumonia, and toxicity of pentamidine.
Brian Wispelwey, Richard D. Pearson
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With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has increased greatly. This review summarizes the pharmacology, clinical experience in the treatment ofPneumocystiscarinii pneumonia, and toxicity of pentamidine.
Brian Wispelwey, Richard D. Pearson
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Annals of Internal Medicine, 1986
Excerpt To the editor: Among the adverse effects of pentamidine, fatal acute pancreatitis has never been reported.
Gérald Simonneau +7 more
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Excerpt To the editor: Among the adverse effects of pentamidine, fatal acute pancreatitis has never been reported.
Gérald Simonneau +7 more
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Ninety Years of Pentamidine: The Development and Applications of Pentamidine and its Analogs
Current Medicinal Chemistry, 2022Abstract: Pentamidine, an FDA-approved human drug for many protozoal infections, was initially synthesized in the late 1930s and first reported to be curative for parasitosis in the 1940s. After ninety years of sometimes quiet growth, pentamidine and its derivatives have gone far beyond antibacterial agents, including but not limited to the ligands of
Bo Zhang +4 more
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Aerosolized Pentamidine and Pregnancy
Annals of Internal Medicine, 1988Excerpt Pentamidine isethionate is an aromatic diamidine-derivative antiprotazoal agent now being used in treatingPneumocystis cariniipneumonia in patients with immunodeficient disease states (1).
Pierre A. Maloley +4 more
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Annals of Internal Medicine, 1984
Excerpt To the editor: In a letter, Sharpe (1) describes the interesting case of a patient withPneumocystis cariniipneumonia who developed hypoglycemia while receiving pentamidine therapy.
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Excerpt To the editor: In a letter, Sharpe (1) describes the interesting case of a patient withPneumocystis cariniipneumonia who developed hypoglycemia while receiving pentamidine therapy.
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Pulmonary Effects of Pentamidine
Annals of Internal Medicine, 1972Excerpt To the editor: We have recently documented the occurrence of diffuse interstitial pulmonary fibrosis in a man after successful treatment of hisPneumocystis cariniipneumonia (1).
Paul K. Hildebrandt +3 more
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Annals of Internal Medicine, 1986
Excerpt To the editor: A recent review on the use of pentamidine (1) outlines the frequent, though usually reversible, renal toxicity associated with this agent.
Matthew Shuster, Mitchell Dunn
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Excerpt To the editor: A recent review on the use of pentamidine (1) outlines the frequent, though usually reversible, renal toxicity associated with this agent.
Matthew Shuster, Mitchell Dunn
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Experimental Parasitology, 1997
Polyamine biosynthesis was studied in wild-type promastigotes of Leishmania donovani and Leishmania amazonensis treated with pentamidine and in the parasites resistant to this drug. Treatment of wild-type clones with low pentamidine concentrations for 24 hr provoked a strong decrease in arginine, ornithine, and putrescine pools, while the level of ...
Basselin, Mireille +3 more
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Polyamine biosynthesis was studied in wild-type promastigotes of Leishmania donovani and Leishmania amazonensis treated with pentamidine and in the parasites resistant to this drug. Treatment of wild-type clones with low pentamidine concentrations for 24 hr provoked a strong decrease in arginine, ornithine, and putrescine pools, while the level of ...
Basselin, Mireille +3 more
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Pentamidine-associated pancreatitis
Digestive Diseases and Sciences, 1989Two patients without risk factors or a prior history of pancreatitis developed acute pancreatitis soon after initiating pentamidine isethionate therapy for Pneumocystis carinii pneumonia associated with the acquired immunodeficiency syndrome. In both patients the pancreatitis improved following medication cessation.
Mitchell S. Schwartz +2 more
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Drug Safety, 1990
With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has greatly increased. This review summarises its pharmacology, its toxicity and clinical experience in the treatment of Pneumocystis carinii pneumonia (PCP).
Richard D. Pearson, Brian Wispelwey
openaire +3 more sources
With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has greatly increased. This review summarises its pharmacology, its toxicity and clinical experience in the treatment of Pneumocystis carinii pneumonia (PCP).
Richard D. Pearson, Brian Wispelwey
openaire +3 more sources