Results 61 to 70 of about 14,249 (201)
Efficacy and safety of a single dose pentamidine (7mg/kg) for patients with cutaneous leishmaniasis caused by L. guyanensis: a pilot study [PDF]
Anais Brasileiros de Dermatologia, 2015 : BACKGROUND: There have been few studies on pentamidine in the Americas; and there is no consensus regarding the dose that should be applied. OBJECTIVES: To evaluate the use of pentamidine in a single dose to treat cutaneous leishmaniasis.
Ellen Priscilla Nunes Gadelha +7 more
doaj +2 more sources
Nanobodies as tools to understand, diagnose, and treat African trypanosomiasis [PDF]
, 2017 African trypanosomes are strictly extracellular protozoan parasites that cause diseases in humans and livestock and significantly affect the economic development of sub-Saharan Africa.
Caljon, Guy +5 more
core +1 more source
International Journal of Rheumatic Diseases, Volume 28, Issue 4, April 2025.ABSTRACT As the world's most rapidly aging society, Japan has faced significant challenges in the management of rheumatoid arthritis (RA) in elderly patients. Biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) have improved disease control, but concerns remain regarding the risk of infection and malignancy, especially in
Koshiro Sonomoto, Yoshiya Tanaka
wiley +1 more source
Pediatric Blood &Cancer, Volume 72, Issue 3, March 2025.ABSTRACT Introduction While clinical practice guidelines (CPGs) for pediatric oncology infection prophylaxis and management exist, few data describe actual management occurring at pediatric oncology centers. Methods An electronic survey querying infection management practices in nontransplant pediatric oncology patients was iteratively created by the ...
Leonora R. Slatnick +28 more
wiley +1 more source
Long‐Term Clinical Outcomes of Paediatric Kidney Transplantation in Hong Kong—A Territory‐Wide Study
Nephrology, Volume 30, Issue 3, March 2025.ABSTRACT Aim To review the clinical characteristics and long‐term outcomes of paediatric kidney transplants in Hong Kong. Method A retrospective cohort study was carried out on all paediatric kidney transplant recipients managed in the Paediatric Nephrology Centre in Hong Kong from 2009 to 2020.
Tsz‐wai Ho +10 more
wiley +1 more source
Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei.
PLoS Neglected Tropical Diseases, 2020 Defining mode of action is vital for both developing new drugs and predicting potential resistance mechanisms. Sensitivity of African trypanosomes to pentamidine and melarsoprol is predominantly mediated by aquaglyceroporin 2 (TbAQP2), a channel ...
Juan F Quintana +5 more
doaj +1 more source
Site- and sequence-selective ultrafast hydration of DNA [PDF]
, 2003 Water molecules in the DNA grooves are critical for maintaining structural integrity, conformational changes, and molecular recognition. Here we report studies of site- and sequence-specific hydration dynamics, using 2-aminopurine (Ap) as the intrinsic ...
Pal, Samir Kumar +3 more
core
, 2011 Artyicle approval pendingHuman African trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease that flourishes in impoverished, rural parts of sub-Saharan Africa. It is caused by infection with the protozoan parasite Trypanosoma brucei and
Chappuis, F, Malvy, D
core +2 more sources
A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li +4 more
wiley +1 more source
Impact of Hepatoblastoma on Infectious Complications Following Pediatric Liver Transplantation
Pediatric Transplantation, Volume 29, Issue 1, February 2025.Our single‐center retrospective study of pediatric patients following liver transplantation (pLT) found that hepatoblastoma (HB) patients had the most infectious events (IE) per patient and were more likely to develop fever & neutropenia than patients with biliary atresia or other hepatic diseases.
Ashton D. Hall +9 more
wiley +1 more source