Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases [PDF]
Glycosylated derivatives of natural product polyphenols display a spectrum of biological activities, rendering them critical for both nutritional and pharmacological applications.
Tuo Li +5 more
doaj +3 more sources
Profiling of primary metabolites and flavonols in leaves of two table grape varieties collected from semiarid and temperate regions [PDF]
Cultivation of grapes in West Bank – Palestine is very old and a large number of grape varieties exist as a result of continuous domestication over thousands of years.
Fernie, A. +11 more
core +2 more sources
One-Pot Hetero-Di-C-Glycosylation of the Natural Polyphenol Phloretin by a Single C-Glycosyltransferase With Broad Sugar Substrate Specificity. [PDF]
Here, an efficient system for synthesizing high‐value polyphenol hetero‐di‐C‐glycosides with two distinct C‐glycosyl residues was established using a two‐step glycosylation catalyzed by C‐glycosyltransferase in one pot. The desired C‐β‐galactosyl‐C‐β‐glucosyl and C‐β‐glucosyl‐C‐β‐xylosyl phloretin were obtained at concentrations of 0.6 and 6 g/L ...
Li T +4 more
europepmc +2 more sources
BackgroundThe lack of understanding of molecular pathologies of the solitary functioning kidney makes improving and strengthening the continuity of care between pediatric and adult nephrological patients difficult.
Xiao Y. Zhou +8 more
doaj +1 more source
Summary Xyloglucan is an abundant polysaccharide in many primary cell walls and in the human diet. Decoration of its α‐xylosyl sidechains with further sugars is critical for plant growth, even though the sugars themselves vary considerably between species. Plants in the Ericales order – prevalent in human diets – exhibit β1,2‐linked xylosyl decorations.
Louis F. L. Wilson +6 more
wiley +1 more source
Genome-wide dissection of co-selected UV-B responsive pathways in the UV-B adaptation of qingke.
Qingke (Tibetan hulless barley) has long been cultivated and exposed to long-term and strong UV-B radiation on the Tibetan Plateau, which renders it an ideal target for elucidating novel UV-B responsive mechanisms.
Xing-Quan Zeng +23 more
semanticscholar +1 more source
Exploring the Unique N-Glycome of the Opportunistic Human Pathogen Acanthamoeba*
Background: Acanthamoeba is a facultative parasite of humans capable of causing keratitis or encephalitis. Results: Novel N-glycan modifications, including core mannosylated fucose, mannose 6-phosphate, and multiple pentose residues, were observed ...
B. Schiller +5 more
semanticscholar +1 more source
Measuring catalytic mechanism similarity – a new approach to study enzyme function and evolution
We introduce a previously undescribed computational method to measure the similarity of enzyme mechanisms, enabling comparison of catalytic steps across hundreds of enzymes. Applying this method to a database of enzyme mechanisms demonstrated its ability to automatically uncover functional and evolutionary relationships, independently of sequence and ...
Antonio J. M. Ribeiro +5 more
wiley +1 more source
Eight common differentially expressed genes/proteins(DEGs/DEPs) of lung tissues and blood samples were identified, including TYMP, LAP3, ADGRL2, SIL1, LMO7, SULF1, ANXA3 and PACSIN3. They may be associated with the inflammation of tuberculosis patients.
Qifeng Li, Kuerbanjiang Maierheba
wiley +1 more source
Rapid detection of hypoxanthine-guanine phosphoribosyltransferase on cellogel
A simple, fast and direct staining method for the detection of hypoxanthineguanine phosphoribosyltransferase is described. It is based on the conversion of inosine monophosphate to hypoxanthine, which is then enzymatically oxidized.
Khan, P.M. +2 more
core

