Results 51 to 60 of about 925 (73)

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt-Dependent NAD⁺ De Novo Synthesis in Mice. [PDF]

Aging Cell
Xu Y, Wang H, Li H, Wei C, Zhu Z, Zhao Y, Zhu J, Lei M, Sun Y, Yang Q.   +9 more
europepmc   +1 more source

Improved efficacy of FKRP AAV gene therapy by combination with ribitol treatment for LGMD2I. [PDF]

Mol Ther, 2023
Cataldi MP, Vannoy CH, Blaeser A, Tucker JD, Leroy V, Rawls R, Killilee J, Holbrook MC, Lu QL.   +8 more
europepmc   +1 more source

mRNA Degradation as a Therapeutic Solution for Mucopolysaccharidosis Type IIIC: Use of Antisense Oligonucleotides to Promote Downregulation of Heparan Sulfate Synthesis. [PDF]

Int J Mol Sci
Santos JI, Gonçalves M, Almeida MB, Rocha H, Duarte AJ, Matos L, Moreira LV, Encarnação M, Gaspar P, Prata MJ, Coutinho MF, Alves S.   +11 more
europepmc   +1 more source

Nucleoside Phosphorylases make N7-xanthosine. [PDF]

Nat Commun
Westarp S, Brandt F, Neumair L, Betz C, Dagane A, Kemper S, Jacob CR, Neubauer P, Kurreck A, Kaspar F.   +9 more
europepmc   +1 more source

Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high-affinity quinolinate binders with a potential role in NAD biosynthesis. [PDF]

FEBS Open Bio
Sorci L, Minazzato G, Amici A, Mazzola F, Raffaelli N.   +4 more
europepmc   +1 more source

Prospective observational study of FKRP-related limb-girdle muscular dystrophy R9: A GRASP consortium study. [PDF]

Ann Clin Transl Neurol
Alfano LN, James MK, Grosfjeld Petersen K, Rudolf K, Vissing J, Augsburger R, Mozaffar T, Jones A, Butler A, Laubscher KM, Mockler SRH, Mathews KD, Iammarino MA, Reash NF, Pietruszewski L, Lowes LP, Strahler T, Wicklund M, Hunn S, Weihl CC, Sasidharan S, Currence M, Statland JM, Stinson N, Holzer M, Leung DG, Lott DJ, Kang PB, Holsten S, Desai U, Johnson NE, GRASP‐LGMD Consortium.   +31 more
europepmc   +1 more source

NAD+ metabolism restriction boosts high-dose melphalan efficacy in patients with multiple myeloma. [PDF]

Blood Adv
Soncini D, Becherini P, Ladisa F, Ravera S, Chedere A, Gelli E, Giorgetti G, Martinuzzi C, Piacente F, Mastracci L, Veneziano C, Santamaria G, Monacelli F, Ghanem MS, Cagnetta A, Guolo F, Garibotto M, Aquino S, Passalaqua M, Bruzzone S, Bellotti A, Duchosal MA, Nahimana A, Angelucci E, Nagasuma C, Nencioni A, Lemoli RM, Cea M.   +27 more
europepmc   +1 more source

Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. [PDF]

Nat Commun
Gawriljuk VO, Godoy AS, Oerlemans R, Welker LAT, Hirsch AKH, Groves MR.   +5 more
europepmc   +1 more source

Structural insights into terminal arabinosylation of mycobacterial cell wall arabinan. [PDF]

Nat Commun
Liu Y, Brown CM, Erramilli S, Su YC, Guu SY, Tseng PS, Wang YJ, Duong NH, Tokarz P, Kloss B, Han CR, Chen HY, Rodrigues J, Khoo KH, Archer M, Kossiakoff AA, Lowary TL, Stansfeld PJ, Nygaard R, Mancia F.   +19 more
europepmc   +1 more source

Genetic blueprint of congenital muscular dystrophies with brain malformations in Egypt: A report of 11 families. [PDF]

Neurogenetics
Safwat S, Flannery KP, El Beheiry AA, Mokhtar MM, Abdalla E, Manzini MC.   +5 more
europepmc   +1 more source