Results 51 to 60 of about 934 (71)

mRNA Degradation as a Therapeutic Solution for Mucopolysaccharidosis Type IIIC: Use of Antisense Oligonucleotides to Promote Downregulation of Heparan Sulfate Synthesis. [PDF]

Int J Mol Sci
Santos JI, Gonçalves M, Almeida MB, Rocha H, Duarte AJ, Duarte AJ, Matos L, Moreira LV, Encarnação M, Gaspar P, Prata MJ, Coutinho MF, Alves S.   +12 more
europepmc   +1 more source

Nucleoside Phosphorylases make N7-xanthosine. [PDF]

Nat Commun
Westarp S, Brandt F, Neumair L, Betz C, Dagane A, Kemper S, Jacob CR, Neubauer P, Kurreck A, Kaspar F.   +9 more
europepmc   +1 more source

Inhibition of xpt Guanine Riboswitch by a synthetic nucleoside analog. [PDF]

PLoS One
Jain SS, McLaughlin EC, Perron GG, Uppuladinne M, Kim S, Gindinova K, Lundgren SH, Elmelech L, Sonavane U, Joshi R, Narasimhulu K.   +10 more
europepmc   +1 more source

Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells. [PDF]

Nat Chem Biol
Li Z, Chawla H, Di Vagno L, Ní Cheallaigh A, Critcher M, Sammon D, Gonzalez-Rodriguez E, Briggs DC, Chung N, Chang V, Mahoney KE, Cioce A, Bineva-Todd G, Wang PY, Liu YC, Murphy LD, Chen YH, Narimatsu Y, Miller RL, Willems LI, Malaker SA, Huang ML, Miller GJ, Hohenester E, Schumann B.   +24 more
europepmc   +1 more source

Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high-affinity quinolinate binders with a potential role in NAD biosynthesis. [PDF]

FEBS Open Bio
Sorci L, Minazzato G, Amici A, Mazzola F, Raffaelli N.   +4 more
europepmc   +1 more source

Prospective observational study of FKRP-related limb-girdle muscular dystrophy R9: A GRASP consortium study. [PDF]

Ann Clin Transl Neurol
Alfano LN, James MK, Grosfjeld Petersen K, Rudolf K, Vissing J, Augsburger R, Mozaffar T, Jones A, Butler A, Laubscher KM, Mockler SRH, Mathews KD, Iammarino MA, Reash NF, Pietruszewski L, Lowes LP, Strahler T, Wicklund M, Hunn S, Weihl CC, Sasidharan S, Currence M, Statland JM, Stinson N, Holzer M, Leung DG, Lott DJ, Kang PB, Holsten S, Desai U, Johnson NE, GRASP‐LGMD Consortium.   +31 more
europepmc   +1 more source

NAD+ metabolism restriction boosts high-dose melphalan efficacy in patients with multiple myeloma. [PDF]

Blood Adv
Soncini D, Becherini P, Ladisa F, Ravera S, Chedere A, Gelli E, Giorgetti G, Martinuzzi C, Piacente F, Mastracci L, Veneziano C, Santamaria G, Monacelli F, Ghanem MS, Cagnetta A, Guolo F, Garibotto M, Aquino S, Passalaqua M, Bruzzone S, Bellotti A, Duchosal MA, Nahimana A, Angelucci E, Nagasuma C, Nencioni A, Lemoli RM, Cea M.   +27 more
europepmc   +1 more source

Dysregulated placental expression of kynurenine pathway enzymes is associated with inflammation and depression in pregnancy. [PDF]

Brain Behav Immun
Sha Q, Escobar Galvis ML, Madaj ZB, Keaton SA, Smart L, Edgerly YM, Anis E, Leach R, Osborne LM, Achtyes E, Brundin L.   +10 more
europepmc   +1 more source

Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. [PDF]

Nat Commun
Gawriljuk VO, Godoy AS, Oerlemans R, Welker LAT, Hirsch AKH, Groves MR.   +5 more
europepmc   +1 more source

<i>XYLT1</i> Deficiency of Human Mesenchymal Stem Cells: Impact on Osteogenic, Chondrogenic, and Adipogenic Differentiation. [PDF]

Int J Mol Sci
Ly TD, Schmidt V, Kühle M, Böker KO, Fischer B, Knabbe C, Faust-Hinse I.   +6 more
europepmc   +1 more source