Results 31 to 40 of about 12,357 (218)
Protective effects of pentoxifylline in small intestine after ischemia–reperfusion
Journal of International Medical Research, 2018 Objective This study was performed to determine the healing effects of pentoxifylline on molecular responses and protection against severe ischemic damage in the small intestine. Methods Thirty-six Wistar albino rats were divided into six groups.
Seracettin Eğin +11 more
doaj +1 more source
Effect of pentoxifylline on kidney damage induced by nitrosamine in male rats
Research in Pharmaceutical Sciences, 2019 Nitrosamines are well-known carcinogenic agents. Humans are exposed to nitrosamines in various ways, the most important of which is the diet. Pentoxifylline is a xanthine derivative, which is used as a drug that inhibits inflammatory factors, reduces ...
Cyrus Jalili +3 more
doaj +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Trials, 2023 Background Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease, with long healing time and a high recurrence rate. It imposes a heavy burden on patients, their families, and the health care system.
Lihong Chen +12 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]
, 1990 Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Schiffl, H. +3 more
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Lasers in Surgery and Medicine, EarlyView.ABSTRACT Objective To evaluate the effects of antimicrobial photodynamic therapy (aPDT), systemic pharmacological therapy, and their combination on irradiated mandibular post‐extraction bone repair relevant to osteoradionecrosis (ORN) development in a rat model. Methods Twenty‐six male Wistar rats were initially randomized into five experimental groups:
Larissa Lopes Fonseca +9 more
wiley +1 more source
Future Journal of Pharmaceutical SciencesBackground Paclitaxel-induced peripheral neuropathy (PIPN) is one of the most common and debilitating toxicity. Up till now, no treatment or preventive medication is recommended by guidelines.
Sondos S. Saleh +3 more
doaj +1 more source
PM&R, EarlyView.Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source
Chemical structure of pentoxifylline.
, 2016 Chemical structure of pentoxifylline.
Beata Talar (551918) +4 more
core +1 more source