Results 31 to 40 of about 444,845 (273)
Impact of Production Linkages on Industrial Upgrading in ASEAN, the People's Republic of China, and India: Organizational Evidence of a Global Supply Chain [PDF]
SSRN Electronic Journal, 2012 This paper presents a simple model of industrial upgrading as a result of backward and forward information linkages between upstream and downstream relations. It also serves as an empirical investigation of the impact of mutual knowledge exchange on the knowledge production function using data on firms' self-reported customers and suppliers.
Machikita, Tomohiro, Ueki, Yasushi
openaire +5 more sources
CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis
Advanced Science, EarlyView.Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou +5 more
wiley +1 more source
Clinical Ophthalmology, 2023 Xiaoe Fan,1,* Junying Li,2,* Gantugs Yundendorj,3 Yajian Duan,4 Shunming Liu,5 Jinghua Jiao,6,7 Lei Liu5 1Department of Ophthalmology, Jincheng People’s Hospital, Jincheng, People’s Republic of China; 2Department of Cataract Surgery, Baotou ...
Fan X +6 more
doaj
Advanced Science, EarlyView.Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu +11 more
wiley +1 more source
The problem of creating a positive image of China on the International arena [PDF]
, 2019 The article is devoted to the research of the problem of forming a positive image of the People’s Republic of China (hereinafter – the PRC) on the International arena.
Andrieieva, K., Karlyuk, S. V.
core
Advanced Science, EarlyView.This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi +11 more
wiley +1 more source
Spatial Price Differences and Inequality in the People's Republic of China: Housing Market Evidence [PDF]
Asian Development Review, 2014 The large literature on regional inequality in the People's Republic of China (PRC) is hampered by incomplete evidence on price dispersion across space, making it hard to distinguish real and nominal inequality.
Chao Li, John Gibson
doaj +1 more source
Advanced Science, EarlyView.Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Processing Trade, Exchange Rates, and the People’s Republic of China’s Bilateral Trade Balances [PDF]
SSRN Electronic Journal, 2011 This paper analyzes the role of processing trade in the People’s Republic of China (PRC)’s bilateral trade balances and the impact of the yuan’s appreciation on processing trade. The analysis is based on panel data covering the PRC’s 51 trading partners from 1993–2008. The empirical analysis shows that: (1) processing trade accounts for 100% of the PRC’
openaire +4 more sources
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
Advanced Science, EarlyView.The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source