Results 11 to 20 of about 66,881 (237)

A stochastic differential equation model for the spread of HIV amongst people who inject drugs [PDF]

, 2016
In this paper, we introduce stochasticity into the deterministic differential equation model for the spread of HIV amongst people who inject drugs (PWIDs) studied by Greenhalgh and Hay [10]. This was based on the original model constructed by Kaplan [17]
Greenhalgh, David, Liang, Yanfeng, Mao, Xuerong   +2 more
core   +8 more sources

Not in the vein: 'missed hits', subcutaneous and intramuscular injections and associated harms among people who inject psychoactive drugs in Bristol, United Kingdom [PDF]

, 2015
Background: The extent of intentional or accidental subcutaneous and intramuscular injections and the factors associated with these have rarely been studied among people who inject drugs, yet these may play an important role in the acquisition bacterial ...
Advisory Council on the Misuse of Drugs, Anonymous, Binswanger, Brett, CDC, Coffin, Darke, European Monitoring Centre for Drugs and Drug Addiction, F. Ncube, Fink, Hankins, Harris, Heckathorn, Heckathorn, Hickman, Hickman, Hope, Hope, Hope, Hope, Hope, J.V. Parry, Judd, Lake, Latkin, Lowy, M. Hickman, MacArthur, Mackenzie, Maliphant, Marks, McColl, Mills, Mullan, Nicoll, Ogston-Tuck, Palmateer, Pieper, Pirozzi, Pizzey, Public Health England, Rhodes, Rhodes, Salganik, Salmon, Scott, Scott, V.D. Hope   +47 more
core   +1 more source

Managing physical health problems in people who inject drugs [PDF]

British Journal of General Practice, 2015
GPs have an important role in addressing the physical health complications of illicit drug use and in particular in people who inject drugs (PWID). Managing these morbidities is within the remit of every GP and does not require any special interest or knowledge.1 A balance will need to be struck between trying to accomplish too much in a single visit ...
O'Donnell, Patrick, Lawson, Euan Malcolm
openaire   +2 more sources

A pragmatic harm reduction approach to manage a large outbreak of wound botulism in people who inject drugs, Scotland 2015 [PDF]

, 2018
Background People who inject drugs (PWID) are at an increased risk of wound botulism, a potentially fatal acute paralytic illness. During the first 6 months of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland, which resulted ...
Amanda Weir, Andrew McAuley, CC McGuigan, CN Ramsay, Corinne Amar, D Akbulut, DJ Passaro, E MacDonald, E Tweed, European Centre for Disease Prevention and Control, Gauri Godbole, Gillian Penrice, GY Chang, Health Protection Scotland, Information Services Division (ISD), J McLauchlin, J Sobel, J Strang, JA Jones, JA Stoltz, K Alpers, K Dunleavy, Kathie Grant, Kirsten M. A. Trayner, Kirsty Roy, M Desai, M Harris, M Ragonnet-Cronin, M Schroeter, MG Booth, N Markwick, National Records of Scotland, NE Palmateer, Public Health England, Health Protection Scotland, Public Health Wales, and Public Health Agency Northern Ireland, RJ Gordon, SB Werner, Scottish Government, Scottish Health Protection Network, SJ Hahné, SR Offerman, TN Wenham, VD Hope, VD Hope, Y Soukup-Baljak   +43 more
core   +1 more source

Examining non-AIDS mortality among people who inject drugs [PDF]

AIDS, 2014
To systematically review and analyse data from cohorts of people who inject drugs (PWID) to improve existing estimates of non-AIDS mortality used to calculate mortality among PWID in the Spectrum Estimates and Projection Package.Systematic review and meta-analysis.We conducted an update of an earlier systematic review of mortality among PWID, searching
Mathers, BM, Degenhardt, L
openaire   +3 more sources

Hepatitis C Virus Vaccines Among People Who Inject Drugs [PDF]

Clinical Infectious Diseases, 2013
Most people who inject drugs (PWID) are infected with hepatitis C virus (HCV), and PWID have the highest risk of HCV infection of any risk group. The incidence of HCV infection is 5%-25% per year, demonstrating continued need for HCV infection prevention in PWID.
Andrea L, Cox, David L, Thomas
openaire   +2 more sources

Association between harm reduction intervention uptake and skin and soft tissue infections among people who inject drugs [PDF]

, 2017
Background: Bacterial skin and soft tissue infections (SSTIs) are a health issue for people who inject drugs (PWID). There is a lack of evidence on the associations between harm reduction (HR) uptake and SSTIs.
Dunleavy, Karen, Goldberg, David, Hutchinson, Sharon, Knox, Tony, Munro, Alison, Palmateer, Norah, Roy, Kirsty, Taylor, Avril   +7 more
core   +5 more sources

Concurrent drug injection during opioid agonist treatment among people who inject drugs in Ukraine [PDF]

Journal of Substance Abuse Treatment, 2018
Ongoing drug use during opioid agonist treatment (OAT) negatively affects treatment and health outcomes, and increases treatment dropout. This study aimed to examine correlates of concurrent illicit drug use among OAT patients in Ukraine. A random sample of 434 patients currently on OAT receiving buprenorphine (BMT) or methadone maintenance treatment ...
Iuliia Makarenko, Alyona Mazhnaya, Ruthanne Marcus, Iryna Pykalo, Lynn Madden, Sergii Filippovich, Sergii Dvoriak, Frederick L. Altice   +7 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source