Results 211 to 220 of about 69,395 (344)

Factors associated with inability to access addiction treatment among people who inject drugs in Vancouver, Canada [PDF]

, 2016

core   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo, Jiayun Liu, Yunxin Su, Tao Jiang, Xincan Wu, Peng Gao, Tao Qin, Mengyuan Wu, Qingqing Li, Shujun Zhang, Baorong He, Yongxiang Wang, Xiaodong Guo, Wei Zhou, Shujie Zhao, Jin Fan, Jian Chen, Guoyong Yin   +17 more
wiley   +1 more source

Understanding drug-related harms as risk-amplifying loops among people who inject drugs in Sweden. [PDF]

Harm Reduct J
Storbjörk J, Samuelsson E, Månsson J, Törrönen J.   +3 more
europepmc   +1 more source

Sono‐Controllable Janus Hydrogel Platform for Sequential Tumor Eradication and Bone Regeneration in Metastatic Breast Cancer

Advanced Science, EarlyView.
Sequential tumor eradication and bone regeneration remain a significant challenge for patients with breast cancer bone metastases. This study develops a novel Janus hydrogel platform, which can achieve tumor elimination and bone repair under the action of different ultrasound frequencies.
Yitong Li, Yunyun Liu, Chuyun Lou, Xuejun Chen, Ying Zhang, Hui Shi, Jiayi Qiu, Shen Zhang, Taixia Wang, Xiaowei Wang, Haohao Yin, Huixiong Xu, Yifeng Zhang   +12 more
wiley   +1 more source

Susceptibility to Hepatitis B Virus Infection Among People Who Inject Drugs in Montreal, Canada. [PDF]

Drug Alcohol Rev
Price O, Larney S, Martel-Laferrière V, Bruneau J, Harney B.   +4 more
europepmc   +1 more source

FGF9–FGFR2 Signaling via Osteocytes‐Preosteoblasts Crosstalks to Mediate Mechanotransduction‐Driven Intramembranous Osteogenesis in the Underdeveloped Maxilla

Advanced Science, EarlyView.
This study identifies osteocyte‐derived FGF9 as a mechanosensitive factor that impairs osteogenesis in the underdeveloped maxilla by inducing FGFR2 nuclear translocation in preosteoblasts. Mechanical stimulation reduces FGF9 secretion, relieving its inhibitory effect. These findings reveal a novel osteocyte–preosteoblast FGF9–FGFR2 axis in craniofacial
Yiwen Zhou, Lili Chen, Miaomiao Han, Peixiang Zhu, Yanyi Wang, Xuanxuan Yu, Tingyu Reng, Huijuan Wang, Baochao Li, Caixia Zhang, Ziwei Huang, Shuang Lin, Guoyun Wang, Jie Ge, Baosheng Guo, Huang Li   +15 more
wiley   +1 more source

The effect of prescription opioid injection on the risk of non-fatal overdose among people who inject drugs [PDF]

, 2015
Stephanie Lake, Kanna Hayashi, Jane A. Buxton, M‐J Milloy, Huiru Dong, Evan Wood, Julio Montaner, Thomas Kerr   +7 more
openalex   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

A look beyond the needle: high prevalence of injecting risk behaviours among people who inject drugs in Zanzibar. [PDF]

BMC Public Health
Kibusi SM, Mohamed KK, Stephano EE, Joho AA, Nyundo A, Mpondo BCT.   +5 more
europepmc   +1 more source

Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe

, 2014
Anneli Uusküla, Mait Raag, Cinta Folch, Leoni Prasad, A Karnite, Maaike G. van Veen, Ksenia Eritsyan, Magdalena Rosińska, Don C. Des Jarlais, Lucas Wiessing   +9 more
openalex   +1 more source