Results 221 to 230 of about 69,395 (344)

Non-fatal overdoses and related risk factors among people who inject drugs in St. Petersburg, Russia and Kohtla-Järve, Estonia [PDF]

, 2015
Anneli Uusküla, Mait Raag, Sigrid Vorobjov, Kristi Rüütel, Alexandra Lyubimova, Olga Levina, Robert Heimer   +6 more
openalex   +1 more source

Senescence‐Inducing Therapy Sequential NIR‐II Mild Photothermal/Senolytic Therapy of Triple Negative Breast Cancer

Advanced Science, EarlyView.
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu, Yehui Kang, Mengdie Yu, Yuejia Ding, Yang Chen, Qingyuan Wu, Yu Cai, Huiyu Liu, Zhenye Lv   +8 more
wiley   +1 more source

"I'm a really hard stick": barriers, facilitators, and preferences in emergency department HIV testing among people who inject drugs. [PDF]

AIDS Care
Adan MA, Psaros C, Kehoe L, Macias-Konstantopoulos WL, Parker RA, Kanjilal D, Fernandes L, Caramazza F, Bassett IV, Ard KL.   +9 more
europepmc   +1 more source

Barriers to practicing risk reduction strategies among people who inject drugs [PDF]

, 2015
Kristina T. Phillips
openalex   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

Advanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen, Jinsi Chen, Li Huang, Xingqiang Lai, Kai Xia, Qiying Lu, Bingbing Xie, Yinong Huang, Yuan Qiu, Tao Wang, Jianqi Feng, Yuanjun Guan, Siyao Che, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source

Rapid Decline in HCV Incidence among People Who Inject Drugs Associated with National Scale-Up in Coverage of a Combination of Harm Reduction Interventions

, 2014
Norah Palmateer, Avril Taylor, David Goldberg, Alison Munro, Celia Aitken, Samantha J. Shepherd, Georgina McAllister, Rory Gunson, Sharon Hutchinson   +8 more
openalex   +2 more sources

Estimating the number of people with hepatitis C virus who have ever injected drugs and have yet to be diagnosed: an evidence synthesis approach for Scotland [PDF]

, 2015
Teresa C. Prevost, Anne M. Presanis, Avril Taylor, David Goldberg, Sharon Hutchinson, Daniela De Angelis   +5 more
openalex   +1 more source

Implementation of low dead space syringes in response to an outbreak of HIV among people who inject drugs: a response to Kesten et al. [PDF]

, 2017
Campbell, John, Goldberg, David J., Hunter, Carole, McAuley, Andrew, Milosevic, Catriona   +4 more
core   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

HIV Incidence among People Who Inject Drugs, San Francisco, 2022. [PDF]

J Acquir Immune Defic Syndr
Elbur AI, Mirzazadeh A, Tate M, Suprasert B, Wilson EC, McFarland W.   +5 more
europepmc   +1 more source