Results 251 to 260 of about 69,395 (344)

Simplified and Integrated Hepatitis C Virus Testing and Treatment Algorithm for Unhoused People Who Inject Drugs. [PDF]

Open Forum Infect Dis
Ramers CB, Vawter N, Northrup A, Klaman SL, Lewis SV, Tam A, Del Aguila C, Lewis R, Mendez B, Reyes L, Matthews E, Rojas S, Godino JG.   +12 more
europepmc   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

Success Metrics for Hepatitis C Elimination Among People Who Inject Drugs: A Scoping Review of Indicators in Harm Reduction. [PDF]

Int J Environ Res Public Health
Kremer DS, Gatmaytan PE, Rübel MA, Flahault A, Hasselgard-Rowe J.   +4 more
europepmc   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source

Prevalence and predictors of condom use among people who inject drugs in Georgia. [PDF]

Harm Reduct J
Kajaia M, Butsashvili M, DeHovitz JA, Kamkamidze G, Gulbiani L, Abzianidze T, Djibuti M.   +6 more
europepmc   +1 more source

Efficacy of a Multi-level Intervention to Reduce Injecting and Sexual Risk Behaviors among HIV-Infected People Who Inject Drugs in Vietnam: A Four-Arm Randomized Controlled Trial

, 2015
Vivian F. Go, Constantine Frangakis, Nguyen Le Minh, Carl A. Latkin, Trần Việt Hà, Tran Thi Mo, Teerada Sripaipan, Wendy Davis, Carla E. Zelaya, Pham The Vu, David D. Celentano, Vu Minh Quan   +11 more
openalex   +2 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

HIV, STI, and Hepatitis Among People Who Inject Drugs at a Sexual Health Clinic in Melbourne, Australia: 2012 to 2022. [PDF]

Open Forum Infect Dis
Phillips TR, Abraham E, Fairley CK, Tan RKJ, Aung ET, Ong JJ, Chow EPF.   +6 more
europepmc   +1 more source

Are Interferon-Free Direct-Acting Antivirals for the Treatment of HCV Enough to Control the Epidemic among People Who Inject Drugs?

, 2015
Viviane D. Lima, Ignacio Rozada, Jason Grebely, Mark Hull, Lillian Lourenço, Bohdan Nosyk, Mel Krajden, Eric M. Yoshida, Evan Wood, Julio Montaner   +9 more
openalex   +2 more sources

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source