Results 261 to 270 of about 69,395 (344)

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source

Hepatitis C virus incidence trend and its risk factors among people who inject drugs in Hai Phong, Vietnam. [PDF]

Hepatol Int
Tran HT, Duong HT, Pham KM, Nguyen BT, Vallo R, D'Ottavi M, Hoang GT, Vu VH, Khuat OTH, Nham TTT, Nguyen DQ, Quillet C, Rapoud D, Van de Perre P, Feelemyer J, Michel L, Laureillard D, Des Jarlais D, Moles JP, Nagot N.   +19 more
europepmc   +1 more source

Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
In ulcerative colitis, the loss of Odoribacter splanchnicus disrupts a microbiota‐metabolite‐neutrophil axis. Restoring this bacterium boosts lithocholic acid, which suppress neutrophil extracellular trap formation and eases colonic inflammation.
Jing Xu, Jianhong Li, Xue Guo, Chen Huang, Yao Peng, Haoming Xu, Yingfei Li, Jingkui Xu, Jinxia Hu, Yitong Liao, Yuqiang Nie, Youlian Zhou   +11 more
wiley   +1 more source

Health and Economic Impact of Periodic Hepatitis C Virus Testing Among People Who Inject Drugs.

JAMA Health Forum
Zhu L, Furukawa NW, Thompson WW, Reitsma MB, Randall LM, Van Handel M, Asher AK, Valverde E, Linas BP, Salomon JA.   +9 more
europepmc   +1 more source

Hepatitis C virus reinfection among people who inject drugs in the country of Georgia and injection-related risk factors: Implications for HCV elimination in the EECA region. [PDF]

PLoS One
Shengelaia L, Anderson EJ, Butsashvili M, Gulbiani L, Kanchelashvili G, Dehovitz J, Djibuti M, Udo T, Kamkamidze G.   +8 more
europepmc   +1 more source

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

Advanced Science, EarlyView.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang, Jingya Dong, Mengyuan Qiu, Jie Bai, Xufeng Cheng, Xiaodong Song   +5 more
wiley   +1 more source

Cutaneous Abscess Prevalence and Risk Factors Among People Who Inject Drugs in Denver, Colorado. [PDF]

Open Forum Infect Dis
Olson NL, Al-Tayyib A, Rowan SE.
europepmc   +1 more source

Epidemiology of Drug Use and HIV-Related Risk Behaviors among People Who Inject Drugs in Mwanza, Tanzania

, 2015
Annabel X. Tan, Saidi Kapiga, Kaveh Khoshnood, R. Douglas Bruce   +3 more
openalex   +2 more sources

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

Advanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li, Peijun Jia, Jingxin Zhang, Huan Zhang, Bing Li, Jiawei Chang, Yating Li, Longzhen Zhao, Yazhe Zhen, Tingting Zheng, Yuanlin Xu, Xiuli An, Shijie Zhang   +12 more
wiley   +1 more source