Results 291 to 300 of about 69,395 (344)

Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study. [PDF]

BMC Public Health
Ghalekhani N, Hajebi A, Ghodusi E, Beygi B, Khojasteh Bojnordi T, Mashhour MF, Rezaei Sharif F, Rajabzadeh F, Khoshdel H, Fathi HR, Sharifi H.   +10 more
europepmc   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Estimating the Population Size of People Who Inject Drugs in 3 Cities in Zambia: Capture-Recapture, Successive Sampling, and Bayesian Consensus Estimation Methods.

JMIR Public Health Surveill
Parmley L, Reid G, Neal JJ, Hanunka B, Tally L, Chilukutu L, Nkumbula T, Mulemfwe C, Chelu L, Handema R, Mwale J, Mutale K, Mulenga L, McIntyre AF, Philip NM, Chung H, Lahuerta M.   +16 more
europepmc   +1 more source

Prevalence and Factors Associated With Sexually Transmitted Infections Among People who Inject Drugs in the San Diego-Tijuana Border Region. [PDF]

Open Forum Infect Dis
Nacht CL, Strathdee SA, Harvey-Vera A, Vera CF, Rangel G, Klausner JD, Artamonova I, Abramovitz D, Skaathun B.   +8 more
europepmc   +1 more source

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source

Social support and HIV management among people who inject drugs: in-depth interviews in Delhi, India. [PDF]

Harm Reduct J
Kaptchuk RP, Kant A, Shekhawat SS, Baishya J, Sinha A, Kedar A, Khanna S, McFall AM, Solomon SS, Mehta SH, Lucas GM.   +10 more
europepmc   +1 more source

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

Advanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang, Mengyu Yu, Linxi Zhu, Neng Tang, Xiao Fu, Zhenghua Cai, Minghao Yan, Yi Chen, Lei Yang, Jianzhuang Wu, Jiatong Tang, Yu Xie, Qi Li, Xu Fu, Liang Mao, Jun Chen, Fanqing Meng, Bo Kong, Xiaodong Han, Chao Yan, Yudong Qiu, Hao Cheng   +21 more
wiley   +1 more source

Current drug use patterns and HIV and HCV prevalence among people who inject drugs in suburban areas of Malaysia. [PDF]

J Int AIDS Soc
Pang J, Danaee M, Balasingam Kasinather V, Des Jarlais D, Kamarulzaman A, Mohd Salleh NA.   +5 more
europepmc   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

Advanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan, Yi Ran, Hong Pan, Qinnan Yan, Wenjing Zhang, Bo Zhou, Pengzhi Xu, Rongdong Liao, Haipeng Xue, Will Jiang, Tailin He, Qingyun Jia, Lei Qin, Francis Y Lee, Di Chen, Chuanju Liu, Guozhi Xiao   +16 more
wiley   +1 more source