Results 301 to 310 of about 69,395 (344)

Characterising people who inject drugs, and association with HIV infection: A situation analysis in Kampala City, Uganda. [PDF]

PLOS Glob Public Health
Mudiope P, Mathers B, Nangendo J, Mutyaba S, Mutamba BB, Alamo S, Nanyenya N, Makumbi F, Laker-Oketta M, Wanyenze R.   +9 more
europepmc   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source

The association between drug injection duration and hepatitis C prevalence among people who inject drugs in Iran. [PDF]

Sci Rep
Haji-Maghsoudi S, Tavakoli F, Mehmandoost S, Nasiri N, Haghdoost AA, Sharifi H.   +5 more
europepmc   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Addressing viral hepatitis C reinfections in a low-threshold programme for people who inject drugs in Slovenia. [PDF]

Harm Reduct J
Černoša J, Volkar JM, Poljak M, Perme MP, Lazarus JV, Matičič M.   +5 more
europepmc   +1 more source

Standardising monitoring data on drug-related infectious diseases among people who inject drugs in Europe - an update of the European Union Drugs Agency technical protocol, 2024. [PDF]

Euro Surveill
Sperle I, Seyler T, Pericoli F, Duffell E, Hutchinson S, Jauffret-Roustide M, Kåberg M, Ķīvīte-Urtāne A, Seguin-Devaux C, Sypsa V, Zimmermann R.   +10 more
europepmc   +1 more source

Infective Endocarditis in People Who Inject Drugs-A 5-Year Follow-up: "I've Seen the Needle and the Damage Done". [PDF]

Open Forum Infect Dis
Halavaara M, Anttila VJ, Järvinen A.
europepmc   +1 more source

Engagement in hepatitis C virus cascade of care and factors associated with testing among people who inject drugs in Iran. [PDF]

Harm Reduct J
Khezri M, Tavakoli F, Mehmandoost S, Sharafi H, Zamani O, Bazrafshani MS, Nasiri N, Mirzaei H, Moameri H, Haghdoost AA, McKnight C, Des Jarlais D, Karamouzian M, Sharifi H.   +13 more
europepmc   +1 more source

Modeling the impact of changing drug markets and structural determinants on HCV and/or HIV transmission among people who inject drugs in the United States: A rural and urban comparison. [PDF]

Int J Drug Policy
Martin NK, Abramovitz D, Eger WH, Friedman JR, Borquez A, Cheema JS, Stamos-Beusig T, Stone J, Vickerman P, Bradley H, Westergaard RP, Strathdee SA.   +11 more
europepmc   +1 more source

Qualitative and quantitative research on preferences and perceptions regarding HIV post-exposure prophylaxis among young women, men, female sex workers, members of the LGBTQ + community and people who inject drugs in Kenya, Nigeria and Zimbabwe. [PDF]

Front Reprod Health
El-Sahn M, Elliott R, El-Sahn M, Garcia-Gurtubay I, Kong K, Wood Santos T, Mulwa R, Muthoka E, Lucas J.   +8 more
europepmc   +1 more source