Results 191 to 200 of about 490,216 (306)

High prevalence of Hepatitis C Virus infection among people who use crack cocaine in an important international drug trafficking route in Central-West Region Brazil

, 2020
Vivianne de Oliveira Landgraf de Castro, Saleem Kamili, Joseph C. Forbi, Andrea Stabile, Elizeu Ferreira da Silva, Sandra Maria do Valle Leone de Oliveira, Paula Renata Tedesco de Carvalho, Marco Antonio Moreira Puga, Tayana Serpa Ortiz Tanaka, Bárbara V. Lago, Mary Luiza Ibanhes, A. Araujo, Alexandra Tejada‐Strop, Yulin Lin, Guoliang Xia, Amanda Sue, Sheila Araújo Teles, Ana Rita Coimbra Motta-Castro   +17 more
openalex   +2 more sources

Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects

Advanced Science, EarlyView.
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su, Jian Qin, Hui Shen, Ling‐Li Zeng, Baojuan Li, Jin Liu, Xuemei Song, Li Liu, Weidan Pu, Tongjian Bai, Huaning Wang, Hong Yin, Kai Wang, Lingjiang Li, Dewen Hu   +14 more
wiley   +1 more source

GRAND PLAN: Safety and Efficacy of Glecaprevir/Pibrentasvir for the Treatment of Hepatitis C Virus Infection Among People Initially Disengaged From Health Care Who Use Drugs—A Systematic Multidisciplinary Approach [PDF]

Brian Conway, Shana Yi, Rossitta Yung, Shawn Sharma   +3 more
openalex   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Preferences for harm reduction vending machine design among rural people who use drugs. [PDF]

Drug Alcohol Depend Rep
Young AM, Jahangir T, Westneat S, Cheatom C, Fallin-Bennett A, Fanucchi LC, Freeman PR, Havens JR, Knudsen HK, McCollister KE, Stitzer S, Stone J, Vickerman P, Livingston MD.   +13 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Perspectives of people who use drugs on implementing overdose response technologies in acute care settings: a qualitative study. [PDF]

Addict Sci Clin Pract
Dhanoa A, Viste D, Rioux W, Seo B, Vasquez M, Vandenberg S, Anhorn C, Ghosh SM.   +7 more
europepmc   +1 more source

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

A Strait or an Ocean? Exploring Risks and Resources among People who use Drugs in Denmark and Sweden. [PDF]

Nordisk Alkohol Nark
Houborg E, Richert T, Nordgren J, Fahnøe KR, Kronbæk M, Kappel N, Johansen KS.   +6 more
europepmc   +1 more source

Mapping the lived experience of rural substance use stigma: A conceptual framework of salient attitudes, beliefs, and behaviors in people who use drugs

Adams L. Sibley, Sophia M. Bartels, Seth M. Noar, Nisha C. Gottfredson, Kathryn E. Muessig, William C. Miller, Vivian F. Go   +6 more
openalex   +2 more sources