Results 1 to 10 of about 19,551 (125)

Structure of the Cytoplasmic Loop between Putative Helices II and III of the Mannitol Permease of Escherichia coli: A Tryptophan and 5-Fluorotryptophan Spectroscopy Study [PDF]

, 2008
In this work, four single tryptophan (Trp) mutants of the dimeric mannitol transporter of Escherichia coli, EIImtl, are characterized using Trp and 5-fluoroTrp (5-FTrp) fluorescence spectroscopy.
Broos J., Broos J., Broos J., Broos J., Broos J., Callis P. R., Chen Y., Cioni P., Eftink M. R., Galley W. C., Gonnelli M., Gonnelli M., Koning R. I., Lakowicz J. R., Legler P. M., Lengeler J. W., Liu T. Q., Meech S. R., Nguyen T. X., Robillard G. T., Robillard G. T., Ross J. B. A., Strambini G. B., Sugiyama J. E., Swaving Dijkstra D., van Montfort B. A., van Montfort R. L. M., Veldhuis G., Veldhuis G., Veldhuis G., Vervoort E. B., Vos E. P., Winkler G. R.   +32 more
core   +13 more sources

Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer

Journal of Experimental & Clinical Cancer Research, 2019
Background The transfer of whole mitochondria that occurs during cell contact has been found to support cancer progression. However, the regulatory role of mitochondria alone is difficult to elucidate due to the complex microenvironment.
Jui-Chih Chang, Huei-Shin Chang, Yao-Chung Wu, Wen-Ling Cheng, Ta-Tsung Lin, Hui-Ju Chang, Shou-Jen Kuo, Shou-Tung Chen, Chin-San Liu   +8 more
doaj   +1 more source

Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation. [PDF]

, 2019
PKM2 is a key metabolic enzyme central to glucose metabolism and energy expenditure. Multiple stimuli regulate PKM2's activity through allosteric modulation and post-translational modifications.
Chen, Tsan-Jan, Cheng, Hsin-Hung, Hsu, Sheng-Chieh, Kung, Hsing-Jien, Liu, Jai-Shin, Liu, Ying-Yuan, Lu, Chien-Hung, Wang, Hung-Jung, Wang, Wen-Ching, Wu, Jing-Wen, Wu, Meng-Chen, Wu, Yu-Fang   +11 more
core   +3 more sources

Protein sorting to mitochondria [PDF]

, 1990
According to the endosymbiont hypothesis, mitochondria have lost the autonomy of their prokaryotic ancestors. They have to import most of their proteins from the cytosol because the mitochondrial genome codes for only a small percentage of the ...
Hartl, Franz-Ulrich, Neupert, Walter
core   +1 more source

Transport of proteins into the various subcompartments of mitochondria [PDF]

, 1992
The import of proteins into mitochondria is an intricate process comprised of multiple steps. The first step involves the sorting of cytosolically synthesized precursor proteins to the mitochondrial surface.
Arretz, Attardi, Baker, Baker, Bartolome Segui-Real, Becker, Cheng, Glick, Hartl, Hartl, Hartl, Hartl, Hauska, Hines, Hwang, Hwang, Kang, Kiebier, Koll, Li, Lill, Mahlke, Martin, Neupert, Ostermann, Ostermann, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Rassow, Rassow, Rassow, Rosemary A. Stuart, Scherer, Schneider, Schneider, Smagula, Steger, Stuart, Stuart, Söllner, Söllner, Söllner, Walter Neupert   +46 more
core   +1 more source

Biogenesis of mitochondrial c-type cytochromes [PDF]

, 1990
Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core   +2 more sources

Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]

, 2004
ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Keller, W., Martin, G.
core   +2 more sources

Molecular Simulations of the Ribosome and Associated Translation Factors

, 2014
The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information.
Hamed H. Alsulami (532535), Muhammad Bilal Ashraf (532534), Muhammad Shahab Alhuthali (532536), Tasawar Hayat (433317)   +3 more
core   +6 more sources

Apocytochrome c [PDF]

, 1990
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout, Böhni, Chen, Cheng, Chirico, Daldal, Deshaies, Deshaies, Drygas, Dumont, Dumont, Eilers, Enosawa, Gabellini, Gabellini, Gasser, Hartl, Hartl, Hawlitschek, Hennig, Hennig, Hennig, Horwich, Horwich, Hurt, Hurt, Jordi, Korb, Lewis, Matsuura, McAda, Meyer, Nargang, Nicholson, Nicholson, Nicholson, Nicholson, Pelham, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pollock, Randall, Rietveld, Rietveld, Rietveld, Rietveld, Rietveld, Rothman, Römisch, Sadler, Schleyer, Schleyer, Schwaiger, Smith, Stewart, Stuart, Stuart, Söllner, Teintze, Welch, Zimmermann, Zimmermann, Zitomer, Zwizinski, Zwizinski   +68 more
core   +1 more source

Endomicroscopic and transcriptomic analysis of impaired barrier function and malabsorption in environmental enteropathy [PDF]

, 2016
Introduction: Environmental enteropathy (EE) is associated with growth failure, micronutrient malabsorption and impaired responses to oral vaccines.
A Prendergast, A Veitch, AC Illing, AJ Prendergast, Alastair Watson, AM Marchiando, AM Marchiando, AM Marchiando, AR Tenorio, B Sandström, Beatrice Amadi, D Gunzel, DI Campbell, E Salazar-Lindo, Ellen Besa, EM Vestergaard, G Marchetti, GC Cook, GT Keusch, J Brenchley, J Vesterbacka, J Zulu, James Lees, JH Humphrey, JM Williams, John Louis-Auguste, JR Turner, Kanekwa Zyambo, L Aamann, L Bremholm, LG Lim, LS Valberg, M Kosek, MH Wojcik, MJ Manary, MM Levine, MS Wapenaar, N Kimer, P Bellot, P Janssen, P Kelly, P Kelly, P Kelly, Paul Kelly, PB Jeppesen, Q Xiao, R Kiesslich, R Kiesslich, RL Guerrant, Rose Soko, Rosemary Banda, S Baldassano, S Tarazona, T Mizuno, Themba Banda, U Trautvetter, V Giorgio, VF Zevallos, W Dhaliwal, WA Petri, William A. Petri, Y Guan   +61 more
core   +5 more sources