Program sustainability post PEPFAR direct service support in the Western Cape, South Africa.
BackgroundPublic health practitioners have little guidance around how to plan for the sustainability of donor sponsored programs after the donor withdraws. The literature is broad and provides no consensus on a definition of sustainability.
Jessica Chiliza +3 more
doaj +8 more sources
Quantifying an Adherence Path-Specific Effect of Antiretroviral Therapy in the Nigeria PEPFAR Program [PDF]
Since the early 2000s, evidence has accumulated for a significant differential effect of first-line antiretroviral therapy (ART) regimens on human immunodeficiency virus (HIV) viral load suppression. This finding was replicated in our data from the Harvard President's Emergency Plan for AIDS Relief (PEPFAR) program in Nigeria.
Eric Tchetgen Tchetgen +2 more
exaly +6 more sources
BackgroundIn 2023, an estimated 1.3 million people newly acquired HIV. In the same year, 3.5 million individuals received pre-exposure prophylaxis (PrEP), falling short of the UNAIDS target of 21.2 million by 2025.
Trena I. Mukherjee +6 more
doaj +5 more sources
The sustainability of public health programs following donor transition: A comparative case study of HIV services and maternal and newborn care in Uganda. [PDF]
Although there is emerging evidence on the impact of donor transition on health programs, there is little research comparing sustainability outcomes across health programs. We sought to compare drivers of health program sustainability concerning maternal
Henry Zakumumpa +5 more
doaj +2 more sources
The Future of the HIV Response: Sustaining Progress in an era of Political Uncertainty and Scientific Opportunity. [PDF]
ABSTRACT The global HIV response is at a pivotal juncture. The field is experiencing a paradox: rapid scientific innovation alongside increasing fragility in financing, political commitment, and implementation systems. Significant progress has been made in expanding access to HIV treatment and prevention, but major gaps in coverage and equity existed ...
Warren M.
europepmc +2 more sources
Impacts of the One Big Beautiful Bill Act on African Public Health Systems. [PDF]
ABSTRACT The enactment of the One Big Beautiful Bill Act (OBBBA) in July 2025 represents a fundamental shift in United States global health financing, with significant implications for African public health systems. For more than three decades, US development assistance for health particularly through initiatives such as the President's Emergency Plan ...
Edward M +6 more
europepmc +2 more sources
Transitioning a large-scale HIV/AIDS treatment program from an international partner to a local Nigerian implementing partner: a before-after early outcomes assessment study [PDF]
Background HIV prevention, treatment, and care across the globe have been heavily dependent on donor funding and international aid, particularly across the Global South, with the highest contribution from the United States Government (USG) through PEPFAR.
David Ochedomi Ekele +17 more
doaj +2 more sources
Analysis of economic and educational spillover effects in PEPFAR countries.
The United States President's Emergency Plan for AIDS Relief (PEPFAR) has been credited with saving millions lives and helping to change the trajectory of the global human immunodeficiency virus (HIV) epidemic.
William Crown +7 more
doaj +1 more source
Ghana’s HIV epidemic and PEPFAR’s contribution towards epidemic control [PDF]
Background: The aim of this review was to summarize the data on HIV/AIDS epidemiology and affected populations in Ghana and to describe the United States President’s Emergency Plan for Emergency Relief’s (PEPFAR) response to the epidemic.
Hammad Ali +8 more
doaj +1 more source
Increases in pediatric antiretroviral treatment, South Africa 2005-2010. [PDF]
BACKGROUND: In South Africa in 2010, about 340,000 children under the age of 15 were infected with HIV. We describe the increase in the treatment of South African pediatric HIV-infected patients assisted by the President's Emergency Plan for AIDS Relief (
Sandeep D Patel +6 more
doaj +1 more source

