Results 41 to 50 of about 142,074 (224)

Helicobacter pylori iceA, clinical outcomes, and correlation with cagA: a meta-analysis. [PDF]

open access: yesPLoS ONE, 2012
Although the iceA (induced by contact with epithelium) allelic types of Helicobacter pylori have been reported to be associated with peptic ulcer, the importance of iceA on clinical outcomes based on subsequent studies is controversial.
Seiji Shiota   +5 more
doaj   +1 more source

Meta-Analysis: Prevalence of Non-Helicobacter pylori, Non-NSAID Peptic Ulcer Disease. [PDF]

open access: yesAliment Pharmacol Ther
A meta‐analysis of 92 studies including 60,816 patients found that non‐H. pylori, non‐NSAID represent a non‐negligible but heterogeneous component of peptic ulcer disease. Among bleeding ulcers, this proportion increased over time, potentially reflecting evolving etiologic patterns beyond H. pylori infection and NSAID exposure.
Watanabe J   +9 more
europepmc   +2 more sources

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen   +10 more
wiley   +1 more source

Is Less More? An Update on Aspirin for Cancer Prevention in Lynch Syndrome From the Cancer Prevention Programme—CaPP

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Aspirin has been used to treat pain and fever for 120 years. Its uses expanded into treating arthritis and prevention of thrombotic events. Its anti‐cancer role emerged with observational studies in the 1980's and subsequent cancer review in those treated with aspirin in cardiovascular trials.
John Burn, D. Timothy Bishop
wiley   +1 more source

Phytotherapeutic modalities for the management of associated peptic ulcer

open access: yesEuropean Journal of Inflammation, 2020
Due to an imbalance between aggressive factors known as hydrochloric acid (HCl), pepsin, leukotrienes, refluxed bile, defensive factors and reactive oxygen species, the peptic ulcer is formed in the stomach and duodenum which mostly include the function ...
Rabia Zahid   +4 more
doaj   +1 more source

Peptic-ulcer disease

open access: yes, 2002
The discovery of Helicobacter pylori has greatly changed our approach to peptic ulcer disease. Bacterial, host, and environmental factors all have a role in peptic-ulcer disease. Although the prevalence of uncomplicated peptic ulcers is falling, hospital
Chan, FKL, Leung, WK
core   +1 more source

Shared Genetic Pathways Linking Oral Diseases to Gastrointestinal Disorders: An Integrative Multi‐Omics Study

open access: yesiMetaMed, EarlyView.
Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang   +6 more
wiley   +1 more source

Anatomical distribution of peptic ulcer in high incidence gastric cancer area

open access: yesRevista de la Facultad de Ciencias de la Salud, 2014
Background: Peptic ulcer makes reference to the solution of continuity of gastric or duodenal wall beyond muscularis mucosae. Previously, duodenal location was more common than gastric, in a ratio ranging from 2:1 to 4:1.
Anuar Alonso Cedeño-Burbano   +4 more
doaj   +2 more sources

Drug-induced peptic ulcer disease [PDF]

open access: yes, 2005
For more than a century, peptic ulcer disease has been a major cause of morbidity and mortality. Peptic ulcer disease is a heterogeneous group of disorders involving the gastrointestinal tract and results from an imbalance between the aggressive forces ...
Vella, Valerie
core  

Recent advances in peptic ulcer bleeding

open access: yes, 2009
Peptic ulcer bleeding remains a common cause of hospital admission, morbidity and mortality. Data published since 2006 illustrate that assessment, endoscopic and pharmacological management, and follow-up strategies can be refined to improve the overall ...
Beales, Ian L. P.
core   +1 more source

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