Results 81 to 90 of about 86,934 (244)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Prevalence and Pattern of Peptic Ulcer Disease among Patients Undergoing Upper Gastrointestinal Endoscopy in Koshi Hospital: A Cross-Sectional Descriptive Study

Journal of Nobel Medical College
Background: Acid peptic disease is one of the most common diseases encountered in outpatient department. There has been limited study on prevalence of different types of peptic diseases among patients undergoing upper gastrointestinal endoscopy ...
Manoj Kumar Thakur, Rohit Kumar Yadav, Rajeshwar Yadav, Priyanka Sharma   +3 more
doaj   +1 more source

Clinically-Endoscopic Manifestations of Peptic Ulcer disease in Children Depending on Helicobacter pylori Infection

Zdorovʹe Rebenka, 2014
We analyzed the clinical and endoscopic features of H.pylori-associated peptic ulcer disease in children. Prevalence of H.pylori-positive cases of peptic ulcer disease, regardless of the localization of ulcers, was determined.
Т.V. Sorokman, S.V. Sokolonyk, М.G. Gingulyak, N.О. Popelyuk   +3 more
doaj   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Assessment of Dietary Pattern for Patients with Peptic Ulcer

Kufa Journal for Nursing Sciences, 2013
Objective: To assess dietary pattern that may contribute to the occurrence of peptic ulcer as risk factors and find out the relationships between dietary pattern indicators and some demographic characteristics (age groups& gender) of the patients with ...
Athra'a karim Hussein AL-Bahadli
doaj   +1 more source

Cytotoxic isolates of Helicobacter pylori from Peptic Ulcer Diseases decrease K+-dependent ATPase Activity in HeLa cells [PDF]

, 2003
Background Helicobacter pylori is a Gram negative bacterium that plays a central role in the etiology of chronic gastritis and peptic ulcer diseases. However, not all H. pylori positive cases develop advanced disease.
JR Warren, Eurogast Study Group, PG Isaacson, AC Wotherspoon, RA Feldman, MJ Blaser, A Lee, MJ Blaser, HLT Mobley, DJ McGee, G Geis, RJ Qwen, TL Cover, LJ van Doorn, Y Yamaoka, J Clemens, A Jain, D Vaira, S Sharma, S Chattopadhyay, S Datta, HH Mollenhauer, ES Reynolds, JHM Willison, DH Tompkins, TL Cover, AA Abdel-Latif, CH Fiske, OH Lowry, V Ricci, PB Ernst, RD Leunk, TL Cover, LJ van Doorn, Y Yamaoka, TM Peters, FB Hoshino, ZJ Pan, Y Yamaoka, H Murakita, M Kidd, KM Fock, AK Mukhopadhyay, S Kumar, SGT Rijpkema, E Papini, DY Graham, DR Cave, M Göõz, MM Levine   +49 more
core   +1 more source

Characteristics, therapeutic pathway and the economic burden of patients with drug‐resistant epilepsy: A real‐world analysis following the introduction of cenobamate in Italy

Epilepsia, EarlyView.
Abstract Objectives Drug‐resistant epilepsy (DRE) remains a major clinical challenge, affecting approximately one‐third of patients with epilepsy. Cenobamate, a novel antiseizure medication (ASM) approved in Italy in 2022, has shown promise in clinical trials. However, real‐world data on its use, especially economic evaluations, remain limited.
Valentina Perrone, Chiara Veronesi, Maria Cappuccilli, Margherita Andretta, Marcello Bacca, Antonietta Barbieri, Fausto Bartolini, Alessandro Brega, Maria Rosaria Cillo, Francesco Colasuonno, Stefania Dell'Orco, Fulvio Ferrante, Stefano Grego, Antonella Lavalle, Daniela Mancini, Maurizio Pastorello, Romina Pagliaro, Cataldo Procacci, Camilla Scandolara, Patrizia Schiavone, Loredana Ubertazzo, Paola Valpondi, Adriano Vercellone, Alberto Zucchi, Maria Ciappetta, Domenico Lucatelli, Andrea Cinti Luciani, Luca Degli Esposti   +27 more
wiley   +1 more source

Helicobacter pylori infection and peptic ulcer in eastern Turkish children: is it more common than known?

The Turkish Journal of Pediatrics, 2011
Helicobacter pylori (H. pylori) infection is mainly acquired in childhood and is frequent in developing countries. The infection is associated with chronic gastritis in all infected children, but peptic ulcer disease develops in a small number of ...
Meltem Uğraş, Ender Pehlivanoğlu
doaj  

Investigation of -308G>A and -1031T>C Polymorphisms in the TNFA Promoter Region in Polish Peptic Ulcer Patients

Gut and Liver, 2014
Background/AimsTumor necrosis factor α (TNF-α) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration. Promoter polymorphisms of TNFA that influence its transcriptional activity and TNF-α production are known. TNFA-
doaj   +1 more source

Helicobacter pylori In Uninvestigated Dyspepsia In Primary Cares In Abakaliki, Nigeria [PDF]

, 2007
There is paucity of information on the prevalence of Helicobacter pylori infection in Nigeria. Enzyme-linked immunosorbent assay (ELISA) was used to determine the prevalence of immunoglobulin G (IgG) antibodies to H.
Ugwu, Nicholas Chukwuka, Ugwuja, Emmanuel Ike   +1 more
core   +1 more source