Results 71 to 80 of about 31,267 (234)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

A Fibreoptic Endoscopic Study of Upper Gastrointestinal Bleeding at Bugando Medical Centre in Northwestern Tanzania: a Retrospective Review of 240 Cases. [PDF]

, 2012
Upper gastrointestinal (GI) bleeding is recognized as a common and potentially life-threatening abdominal emergency that needs a prompt assessment and aggressive emergency treatment.
Wolfgang Scheppach, Koy Mheta, Kabangila Rodrick, Mirambo, M, Rodrick Kabangila, Scheppach Wolfgang, Phillipo L Chalya, Mirambo, Mariam, Chalya Phillipo L, Liwa, Anthony, Jaka Hyasinta, Mchembe Mabula D, Jaka, H., McHembe, M.D., Koy, Mheta, Scheppach, W., Mkongo Eliasa, Jaka, Hyasinta, Liwa Anthony, Eliasa Mkongo, Mirambo Mariam, Mabula D Mchembe, Mariam Mirambo, Liwa, A., Anthony Liwa, Scheppach, Wolfgang, Chalya, Phillipo L, Chalya, P.L., McHembe, Mabula D, Kabangila, Rodrick, Koy, M., Hyasinta Jaka, Mheta Koy, Mkongo, E., Kabangila, R., Mkongo, Eliasa   +35 more
core   +1 more source

Peptic ulcer in the gallbladder. A case report

, 1985
Gastric mucosa can be found in the gallbladder as a congenital heterotopia. A case of a perforated peptic ulcer in the gallbladder with concomitant hemorrhage in heterotopic gastric mucosa causing hematemesis and melena is presented.
Larsen, E H, Diederich, P J, Sørensen, Flemming Brandt   +2 more
core   +1 more source

Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review

Hemodialysis International, EarlyView.
ABSTRACT Background Gastrointestinal bleeding is very common among hemodialysis patients. This high bleeding risk is caused by uremic platelet dysfunction, vascular fragility, intradialytic hemodynamic instability, and widespread antithrombotic therapy.
Andreas Smyrlis, Konstantia Kantartzi, Konstantinos Mimidis, Stylianos Panagoutsos   +3 more
wiley   +1 more source

Trends in peptic ulcer disease and the identification of Helicobacter Pylori as a causative organism: Population-based estimates from the US nationwide inpatient sample

, 2018
Background: Peptic ulcer disease can lead to serious complications including massive hemorrhage or bowel perforation. The modern treatment of peptic ulcer disease has transitioned from the control of gastric acid secretion to include antibiotic therapy ...
Nahed, Brian, Redjal, Navid, Walcott, Brian, Kahle, Kristopher T., Bashinskaya, Bronislava   +4 more
core   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and the Risk of Periodontitis Among Adults With Osteoarthritis: A Target Trial Emulation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) may mitigate periodontal tissue breakdown through cyclooxygenase (COX) inhibition; however, their long‐term effects on the risk of periodontitis remain unclear. Methods We emulated target trials using US electronic health records (1995–2019) to compare the 5‐year risk of incident ...
Ignacio Leiva‐Escobar, Aiswarya Puzhakkara Chennas, Zoheir Alayash, Stefan Lars Reckelkamm, Birte Holtfreter, Thomas Kocher, Sebastian‐Edgar Baumeister, Michael Nolde   +7 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

[Treatment of complicated peptic ulcer: personal experience]

, 2003
BACKGROUND The availability of drugs which can effectively inhibit gastric secretion allowed the control of the peptic disease in almost all the patients, but the incidence of complications is substantially unchanged.
Ugolini G, Pasqualini E, Peruzzi S, Catena F, Campione, De Bonis F, Caira A   +6 more
core  

Gastroduodenal artery embolization for peptic ulcer hemorrhage refractory to endoscopic intervention: A single-center experience. [PDF]

J Clin Imaging Sci, 2022
Khazi ZM, Marjara J, Nance M, Ghouri Y, Hammoud G, Davis R, Bhat A.   +6 more
europepmc   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source