Results 161 to 170 of about 1,445,844 (265)

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I. [PDF]

Discov Immunol
Murali TM, Li B, Hoos E, Collinson L, Long EO, Dushek O, Elliott T, Sim MJW.   +7 more
europepmc   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Persistence of proinsulin-only secretion in people with long-duration diabetes and minimal residual insulin secretion. [PDF]

Diabet Med
Metghalchi S, Bonnet-Serrano F, Alexandre L, Daclin S, Akiki V, Laguillier-Morizot C, Dehghani L, Zientek C, Leguy MC, Mallone R, Guibourdenche J, Larger E.   +11 more
europepmc   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

Advanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross, Ryan Gharios, Shivani Kottantharayil, Cole A. DeForest   +3 more
wiley   +1 more source

Enzyme-Free Phosphorylation with Kinetic Gating in a De Novo Coiled-Coil System. [PDF]

J Am Chem Soc
Poprawa SM, Hoja NL, Hipp C, King RO, Soria-Carrera H, Woolfson DN, Sattler M, Kaila VRI, Boekhoven J.   +8 more
europepmc   +1 more source

Hybrid Amyloid–Boron Nitride Aerogels for Lightweight Sound Insulation

Advanced Materials, EarlyView.
Amyloid fibrils template the mild formation of boron nitride–rich hybrid aerogels with hierarchical porosity, enhanced BN‐like ordering, and fibril‐reinforced mechanics. These ultralight materials combine thermal stability with strong sound absorption and transmission loss, offering a sustainable bio‐assisted route toward lightweight acoustic shields ...
Mohammad Peydayesh, Andrin Lustgarten, Stefan Schoenwald, Enrico Boschi, My Hanh Bui, Ali Miserez, Felix Donat, Christoph R. Müller, Raffaele Mezzenga   +8 more
wiley   +1 more source

Radiolabeled Angiopep-2 Peptide Vector as a Preclinical Platform for Blood-Brain Barrier Targeting: Synthesis, Radiolabeling, and Preliminary In Vivo Biodistribution in Mice. [PDF]

J Pept Sci
Fotou E, Apostolopoulou A, Bika CG, Giannakopoulou M, Bajwa DE, Moussis V, Tsikaris V, Gerothanassis IP, Alexiou GA, Bouziotis P, Tzakos AG.   +10 more
europepmc   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Double-Stapled Peptide Scan Yields Potent Fusion Inhibitors of Respiratory Syncytial Virus. [PDF]

J Med Chem
Pidoux N, Roh L, Nicolet N, Marti R, Le Rouzic A, Prompt C, Fix J, Duquerroy S, Rey F, Rameix-Welti MA, Keck M, Barbe P, Garcin D, Mottet-Osman G, Larcher T, Galloux M, Nyanguile O.   +16 more
europepmc   +1 more source