Results 131 to 140 of about 355,998 (353)

Key for mutant human IAPP peptide sequences and cleaved fragments.

, 2016
Key for mutant human IAPP peptide sequences and cleaved fragments.
Jonitha Gardner (328549), Helene Baribault (328546), Ping Cao (564151), Li Miao (734548), Trace Tsuruda (2011873), Yang Li (7082), Linda Huang (2141800), Kui Chen (157443), Xiaosu Wu (756219), Jed Wiltzius (2141794), Ryan D. White (1656982), Oliver Homann (2141806), Harvey Yamane (559007), Ingrid C. Rulifson (2141809), Kim Samayoa (2141803), David Kopecky (2141812), Tim Carlson (2141797)   +16 more
core   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Erratum to: Synthetic Peptide Fragments of the Wtx Toxin Reduce Blood Pressure in Rats under General Anesthesia. [PDF]

Dokl Biochem Biophys, 2023
Severyukhina MS, Ismailova AM, Shaykhutdinova ER, Dyachenko IA, Egorova NS, Murashev AN, Tsetlin VI, Utkin YN.   +7 more
europepmc   +1 more source

Probing the binding of the coumarin drugs using peptide fragments of DNA gyrase B protein

, 2005
Bacterial DNA gyrase, has been identified as the target of several antibacterial agents, including the coumarin drugs. The coumarins inhibit the gyrase action by competitive binding to the ATP-binding site of DNA gyrase B (GyrB) protein.
E. Trovatti, Marchetto, Reinaldo [UNESP], Garrido, Saulo Santesso, Marchetto, Reinaldo, A. C. Scatigno, D.C. Carvalho, Scatigno, A. C., Garrido, Saulo Santesso [UNESP], Trovatti, E., Carvalho, D. C. [UNESP], Trovatti, E. [UNESP], R. Marchetto, Carvalho, D. C., S.S. Garrido   +13 more
core   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Synthetic Peptide Fragments of the Wtx Toxin Reduce Blood Pressure in Rats under General Anesthesia. [PDF]

Dokl Biochem Biophys, 2023
Severyukhina MS, Ismailova AM, Shaykhutdinova ER, Dyachenko IA, Egorova NS, Murashev AN, Tsetlin VI, Utkin YN.   +7 more
europepmc   +1 more source

Molecular dynamics simulation of the phosphorylation-induced conformational changes of a tau peptide fragment [PDF]

, 2014
Albert J. Lyons, Neha S. Gandhi, Ricardo L. Mancera   +2 more
openalex   +1 more source

Simultaneous and Traceless Ligation of Peptide Fragments on DNA Scaffold

, 2019
Peptide ligation is an indispensable step in the chemical synthesis of target peptides and proteins that are difficult to synthesize at once by a solid-phase synthesis.
Akimitsu Okamoto (241019), Masafumi Yanase (1634785), Gosuke Hayashi (1580665), Yu Nakatsuka (6312908)   +3 more
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Natriuretic peptides: Diagnostic and therapeutic use

Indian Journal of Endocrinology and Metabolism, 2011
Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit, Pradip Mukhopadhyay, Sujoy Ghosh, Subhankar Chowdhury   +3 more
doaj   +1 more source