Results 261 to 270 of about 379,196 (358)

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source

DNA encoded peptide library for SARS-CoV-2 3CL protease covalent inhibitor discovery and profiling. [PDF]

RSC Chem Biol
Xing Y, Zhang H, Wang Y, Zong Z, Bogyo M, Chen S.   +5 more
europepmc   +1 more source

A Novel Peptide Isolated from a Phage Display Library Inhibits Tumor Growth and Metastasis by Blocking the Binding of Vascular Endothelial Growth Factor to Its Kinase Domain Receptor [PDF]

, 2002
Hetian Lei, Ping An, Song Shumei, Xiaoying Liu, He Luowen, Wu Jian, Meng Lin, Liu Meisheng, Jun‐Shan Yang, Chengchao Shou   +9 more
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library.

Cell Chem Biol, 2021
Emery A, Hardwick BS, Crooks AT, Milech N, Watt PM, Mithra C, Kumar V, Giridharan S, Sadasivam G, Mathivanan S, Sudhakar S, Bairy S, Bharatham K, Hurakadli MA, Prasad TK, Kamariah N, Muellner M, Coelho M, Torrance CJ, McKenzie GJ, Venkitaraman AR.   +20 more
europepmc   +1 more source

Study into the cyclization of an epoxy-alcohol to the energetically disfavored product by peptides from non-biased combinatorial libraries

, 2000
Gabriela Chiosis
openalex   +1 more source

Immunogenically Fit Subunit Vaccine Components Via Epitope Discovery from Natural Peptide Libraries [PDF]

, 2002
Leslie J. Matthews, Robert D. Davis, George P. Smith   +2 more
openalex   +1 more source

Fully Automated Deep Learning Enabled Miniature Mass Spectrometry System for Psychoactive Therapeutic Drug Monitoring

Advanced Science, EarlyView.
This study presents a fully automated miniature mass spectrometry system for high‐throughput therapeutic drug monitoring. Integrating magnetic solid‐phase extraction, self‐aspiration sampling miniature mass spectrometer, and U‐net deep learning quantitative algorithm, it achieves rapid (8 samples/30 min), precise (R2 > 0.99, RSD < 10%), and portable ...
Yuanhao Zhou, Jiawen Ai, Zi Ye, Kexin Chen, JingXiong Lin, Zhenhua Zhang, Mi Luo, Benjie Zhou, Shijian Xiang, Jianhua Zhou, Xinming Huo   +10 more
wiley   +1 more source

A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane-containing Building Block Leads to Thiol-independent Inhibitors of Phosphoglycerate Mutase. [PDF]

Chem Asian J, 2020
Okuma R, Kuwahara T, Yoshikane T, Watanabe M, Dranchak P, Inglese J, Shuto S, Goto Y, Suga H.   +8 more
europepmc   +1 more source

Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides [PDF]

, 2002
Ola Larsson
openalex   +1 more source