Results 121 to 130 of about 611,085 (327)
Templated Synthesis of Peptide Nucleic Acids via Sequence-Selective Base-Filling Reactions [PDF]
, 2015 Templated Synthesis of Peptide Nucleic Acids via Sequence-Selective Base-Filling ...
David R. Liu (220122) +1 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Тонкие химические технологии, 2007 A cytosine-containing monomer for negatively charged peptide nucleic acids has been prepared for the first time, and the ways of its synthesis have been optimized.
A. V. Baranov +5 more
doaj
Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters [PDF]
, 2010 Antigene RNAs (agRNAs) are small RNA duplexes that target non-coding transcripts rather than mRNA and specifically suppress or activate gene expression in a sequence-dependent manner.
Charisse, Klaus +6 more
core +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Peptide Nucleic Acid Synthons [PDF]
, 2004 A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide ...
Engholm, Michael +3 more
core
α-Helical Peptide Nucleic Acids (αPNAs): A New Paradigm for DNA-Binding Molecules [PDF]
, 2016 α-Helical Peptide Nucleic Acids (αPNAs): A New Paradigm for DNA-Binding ...
Philip Garner (1831117) +2 more
core +1 more source
Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants
Advanced Science, EarlyView.A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei +8 more
wiley +1 more source
Scientific ReportsThe human cathelicidin host defense peptide LL-37 is expressed by many cell types, including neutrophils, macrophages, and epithelial cells, and forms complexes with nucleic acids that can have either beneficial or detrimental health effects.
Claudia Zielke +9 more
doaj +1 more source
Chiral Peptide Nucleic Acids with a Substituent in the N-(2-Aminoethy)glycine Backbone
Molecules, 2012 A peptide nucleic acid (PNA) is a synthetic nucleic acid mimic in which the sugar-phosphate backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and RNA with higher affinity and superior sequence selectivity compared to DNA ...
Atsushi Kittaka, Toru Sugiyama
doaj +1 more source