Results 141 to 150 of about 855,791 (338)

Improving binding affinity through cyclization [PDF]

, 2017
Cancer chemotherapy results in systematic damage as the drugs used are also toxic to benign tissue. Sensitizing a cancer cell to therapy by interfering with the DNA repair mechanisms would decrease overall toxicity, as the necessary dosage of ...
Abrigo, Nicolas, Newcomb, Kaylee M
core   +1 more source

Carnosine–anserine synthetase of muscle. 4. Partial purification of the enzyme and further studies of β-alanyl peptide synthesis [PDF]

, 1960
J. Stenesh, Theodore Winnick
openalex   +1 more source

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

Protease-Resistant, Broad-Spectrum Antimicrobial Peptides with High Antibacterial and Antifungal Activity

Life
Antimicrobial peptides (AMPs) are a diverse group of small, naturally occurring molecules that orchestrate the innate immune response of various organisms, from microorganisms to humans.
Tanil Kocagoz, Betul Zehra Temur, Nihan Unubol, Merve Acikel Elmas, Zeynep Kanlidere, Sumeyye Cilingir, Dilan Acar, Gizem Boskan, Sumeyye Akcelik Deveci, Esma Aybakan, Aslihan Ozcan Yoner, Neval Yurttutan Uyar, Mustafa Serteser, Seray Sahsuvar, Yigit Erdemgil, Zeynep Zulfiye Yildirim Keles, Deniz Demirhan, Sandra Sakalauskaite, Rimantas Daugelavicius, Tugba Arzu Ozal Ildeniz, Ahmet Emin Atik, Erkan Mozioglu, Tarik Eren, Serap Arbak, Guldal Suyen, Ozge Can   +25 more
doaj   +1 more source

Biofilm Control by Active Topography with Mucin Coating

Advanced Functional Materials, EarlyView.
This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han, Yikang Xu, Huan Gu, Teng Zhang, Dacheng Ren   +4 more
wiley   +1 more source

Ac-[K-Aib-C(3,9-Acm; 6,12-DFLC_(Acm)KKESEK)]₄-NH₂

Molbank
Chemoselective reactions have played a crucial role in the development of high-molecular-weight (>3000 Da) macromolecules with a branched architecture, particularly as peptides and epitope-based vaccines have emerged as promising tools for drug ...
Vasiliki Moulasioti, Evgenia Fotou, Vassilios Moussis, Vassilios Tsikaris   +3 more
doaj   +1 more source

Catalysis in Peptide Synthesis with Active Esters. II. Effects of Concentrated Carboxylic Acids on the Aminolysis of Benzyloxycarbonyl-L-phenylalaninep-Nitrophenyl Ester in Dioxane [PDF]

, 1969
Nobuhiro Nakamizo
openalex   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

Cell Membrane Vesicle Camouflaged Artificial Cells

Advanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres, Stefan Pendlmayr, Noga Gal, Cathrine Abild Meyer, Cecilie Ryberg, Olav Vestrheim, Noel Angelo Kalacas, Fatih Demir, Markus M. Rinschen, Karsten Haupt, Rajeshwar Prosad Mookerjee, Brigitte Städler   +11 more
wiley   +1 more source

Studies of the Synthesis of Peptides Containing C-Terminal Glutamine. II The Synthesis and Use of α-p-Nitrobenzyl γ-Methyl l-Glutamate [PDF]

, 1964
Yasutsugu Shimonishi
openalex   +1 more source