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The Immunochemistry of Peptidoglycan
European Journal of Biochemistry, 1974A pentapeptide, Gly‐l‐Ala‐l‐Ala‐d‐Ala‐d‐Ala, was synthesized and covalently linked with its free amino group to human serum albumin. Immunization of rabbits with this albumin‐peptide conjugate yielded antisera containing predominantly antibodies directed against the peptide. By means of inhibition studies with various amino‐aicd derivatives and related
Peter H. Seidl, Karl H. Schleifer
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The role of peptidoglycan in pathogenesis
Current Opinion in Microbiology, 2005Bacterial pathogens rely on a variety of virulence factors to establish the colonization of a new niche. Although peptidoglycan and its muropeptide derivatives have been known to possess potent biological properties, until recently the molecular bases were poorly understood.
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A competitive radioimmunoassay for peptidoglycan monomer
Clinica Chimica Acta, 1991The preparation and characterization of the essential components to be used in the radioimmunoassay of peptidoglycan monomer (PGM) is described. In order to raise the anti-peptidoglycan monomer antibodies 14C-labelled peptidoglycan monomer-bovine serum albumin conjugate was prepared by the coupling of 14C-peptidoglycan monomer to bovine serum albumin ...
Branka Vranešić+3 more
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2015
Peptidoglycan is an essential component of the bacterial cell envelope and protects the cell from bursting due to turgor and maintains cell shape. Composed of glycan chains connected by short peptides, peptidoglycan forms a net-like macromolecule around the cytoplasmic membrane.
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Peptidoglycan is an essential component of the bacterial cell envelope and protects the cell from bursting due to turgor and maintains cell shape. Composed of glycan chains connected by short peptides, peptidoglycan forms a net-like macromolecule around the cytoplasmic membrane.
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Peptidoglycan in eukaryotes: Unanswered questions
Phytochemistry, 2020Peptidoglycan has been retained in chloroplasts that have evolved from cyanobacteria along some evolutionary tracks, but has seemingly been quickly eliminated during evolution of others. It has been eliminated in Rhodophyta, Chlorophyta, Pteridophyta and Spermatophyta, but has been retained in streptophyte algae, Glaukophyta, and Lycophyta.
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Regulation of peptidoglycan synthesis and remodelling
Nature Reviews Microbiology, 2020Alexander J F Egan+2 more
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Peptidoglycane bei Pyelonephritis [PDF]
Bei einem Teil der Patienten mit chronischer Pyelonephritis lassen sich im Harn keine vermehrten Bakterienzahlen nachweisen. Auch das Nierengewebe selbst ist bakteriologisch negativ. Trotzdem schreitet der destruierende Entzundungsprozes im Nierenparenchym fort.
H. D. Marquardt, B. Heymer, W. Naewie
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Detection of peptidoglycans by NOD proteins
Trends in Cell Biology, 2003Mechanisms of innate immune defense are based on the recognition of invariant microbial molecular patterns by specific receptors, followed by the activation of signaling pathways and the expression of effector molecules that will defeat the invading microorganism.
Jean-Marc Reichhart, Julien Royet
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2011
Information on the peptidoglycan structure is an indispensable component for the description of new genera of Gram-positive bacteria. In certain genera, structural variations of the peptidoglycan support even the differentiation at the species level. The analysis of the peptidoglycan requires the isolation and purification of this three-dimensionally ...
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Information on the peptidoglycan structure is an indispensable component for the description of new genera of Gram-positive bacteria. In certain genera, structural variations of the peptidoglycan support even the differentiation at the species level. The analysis of the peptidoglycan requires the isolation and purification of this three-dimensionally ...
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Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling
Nature, 2020Elizabeth J. Culp+10 more
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