Results 181 to 190 of about 1,975,266 (317)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Unit roots and multiple structural breaks in real output [PDF]
Utilizing re-sampling. Methods, we present evidence on the rejection probabilities for difference-stationary and trend-stationary models for Mexico’s real and real per-capita annual gross domestic product.
Araceli Ramírez-Zamora +1 more
core
Maximizing SNR per unit time in diffusion MRI with multiband T-Hex spirals. [PDF]
Magn Reson MedEngel M +4 more
europepmc +1 more source
Maximizing NMR signal per unit time by facilitating the e-e-n cross effect DNP rate. [PDF]
Phys Chem Chem Phys, 2018 Leavesley A +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Are Shocks to Commodity Prices Persistent? [PDF]
This paper considers the issue of whether shocks to ten commodity prices (gold, silver, platinum, copper, aluminum, iron ore, lead, nickel, tin, and zinc) are persistent or transitory. We use two recently developed unit root tests, namely the Narayan and
Ruipeng Liu, Paresh Kumar Narayan
core
New mechanism to identify cost savings in English NHS prescribing: minimising 'price per unit', a cross-sectional study. [PDF]
BMJ Open, 2018 Croker R +5 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source