Results 11 to 20 of about 1,139,122 (202)

Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case-Control Study and Call for a Consensus. [PDF]

Ann Neurol
[Color figure can be viewed at www.annalsofneurology.org] Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
B Szabo A, Curot J, Gérard F, Rulquin F, Debs R, Georges C, Denuelle M, Bouloufa A, Lemesle B, Péran P, Thalamas C, Barbeau EJ, Pariente J, Dahan L, Valton L.   +14 more
europepmc   +2 more sources

Deep Learning to Differentiate Parkinsonian Syndromes Using Multimodal Magnetic Resonance Imaging: A Proof-of-Concept Study. [PDF]

Mov Disord
Abstract Background The differentiation between multiple system atrophy (MSA) and Parkinson's disease (PD) based on clinical diagnostic criteria can be challenging, especially at an early stage. Leveraging deep learning methods and magnetic resonance imaging (MRI) data has shown great potential in aiding automatic diagnosis.
Mattia GM, Chougar L, Foubert-Samier A, Meissner WG, Fabbri M, Pavy-Le Traon A, Rascol O, Grabli D, Degos B, Pyatigorskaya N, Faucher A, Vidailhet M, Corvol JC, Lehéricy S, Péran P.   +14 more
europepmc   +2 more sources

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20-93: The INSPIRE-T Project. [PDF]

Aging Cell
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Lu WH, Guyonnet S, Raffin J, Bessou-Touya S, Helffer KR, Bianchi P, Digabel JL, Bensadoun P, Lemaitre JM, Barreto PS, Vellas B, IHU HealthAge INSPIRE/Open Science study group.   +11 more
europepmc   +2 more sources

Structural Alterations Associated With Cardiovascular Autonomic Failure in Multiple System Atrophy. [PDF]

Eur J Neurol
ABSTRACT Background Early severe autonomic failure (AF) in multiple system atrophy (MSA) is a risk factor for poor survival. Postmortem studies suggested that AF is related to the degeneration of preganglionic autonomic neurons of the brainstem and spinal cord. Objectives Characterize cerebral alterations on brain imaging associated with cardiovascular
Georges C, Arribarat G, Kermorgant M, Bonneville F, Fabbri M, Foubert A, Meissner W, Rascol O, Traon AP, Péran P.   +9 more
europepmc   +2 more sources

Disease Progression in Multiple System Atrophy: The ASPIRE Multi-Modal Biomarker Study. [PDF]

Ann Neurol
Objective The objective of this study was to characterize changes in candidate biomarkers in early multiple system atrophy (MSA) and identify baseline predictors of faster progression. Methods This 1‐year, multicenter, prospective study assessed clinical, neuroimaging (3T‐magnetic resonance imaging [MRI], dopamine transporter single‐photon emission ...
Fabbri M, Del Campo N, Meissner WG, Rousseau V, Sommet A, Payoux P, Gantet P, Drif A, Catalá H, Thalamas C, Tranchant C, Durif F, Marques A, Eusebio A, Defebvre L, Corvol JC, Thobois S, Flaus A, Corbille AG, Frismand S, Patterson B, Foubert-Samier A, Traon AP, Arribarat G, Péran P, Rascol O, ASPIRE Study Group.   +26 more
europepmc   +2 more sources

Trajectories of Pontine Volume in Patients with Multiple System Atrophy. [PDF]

Mov Disord
Abstract Objectives To investigate trajectories of regional brain volume changes in multiple system atrophy (MSA) and their potential utility as surrogate markers of disease progression in the cerebellar subtype (MSA‐C). Background Reliable biomarkers for tracking disease progression in MSA are urgently needed.
Kawabata K, Krismer F, Ito M, Hara K, Bagarinao E, Beliveau V, Péran P, Arribarat G, Traon AP, Meissner WG, Foubert-Samier A, Fabbri M, Gordon MF, Ogura A, Katsuno M, Rascol O, Scherfler C, Seppi K, Watanabe H, Poewe W.   +19 more
europepmc   +2 more sources

Lifespan Tree of Brain Anatomy: Diagnostic Values for Motor and Cognitive Neurodegenerative Diseases. [PDF]

Hum Brain Mapp
The lifespan tree of brain anatomy improves multiclass differential diagnosis of neurodegenerative diseases by modeling brain volume changes over time. It outperforms SVM, provides interpretable disease trajectories, and enhances real‐world clinical applicability.
Coupé P, Mansencal B, Manjón JV, Péran P, Meissner WG, Tourdias T, Planche V.   +6 more
europepmc   +2 more sources

Three-dimensional conservation planning of fish biodiversity metrics to achieve the deep-sea 30×30 conservation target. [PDF]

Conserv Biol
Abstract Accelerating rate of human impact and environmental change severely affects marine biodiversity and increases the urgency to implement the Convention on Biological Diversity (CBD) 30×30 plan for conserving 30% of sea areas by 2030. However, area‐based conservation targets are complex to identify in a 3‐dimensional (3D) ocean where deep‐sea ...
Mathon L, Baletaud F, Lebourges-Dhaussy A, Lecellier G, Menkes C, Bachelier C, Bonneville C, Dejean T, Dumas M, Fiat S, Grelet J, Habasque J, Manel S, Mannocci L, Mouillot D, Peran M, Roudaut G, Sidobre C, Varillon D, Vigliola L.   +19 more
europepmc   +2 more sources

Revitalisasi peran dan fungsi perpustakaan perguruan tinggi (pendekatan pengembangan perpustakaan di masa islam klasik)

Pustaka Karya: Jurnal Ilmiah Ilmu Perpustakaan dan Informasi, 2021
Penelitian ini bertujuan untuk mengkaji perpustakaan yang paling menonjol pada masa Islam klasik berdasarkan sejarah Islam. Islam pada zaman keemasannya pernah menjadi peradaban yang paling maju di dunia. Penelitian berjenis kualitatif deskriptif di mana
Hamidi Ilhami, Moch Isra Hajiri
doaj   +1 more source

Pengaruh Ambiguitas Peran dan Konflik Peran Terhadap Kreativitas Karyawan

Jurnal Bisnis dan Manajemen, 2020
This research aims to determine the influence of role ambiguity and role conflict on employee creativity. This research used the causal method by collecting primary data obtained through distributing questionnaires. Samples are 126 respondents of Faculty Economics and Business University Lampung alumnae who graduated 2015-2017.
Dina Safitri, Keumala Hayati,, Ribhan Ribhan,, Petrus Hasiholan Tamba,   +3 more
openaire   +2 more sources