Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case-Control Study and Call for a Consensus. [PDF]
[Color figure can be viewed at www.annalsofneurology.org] Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
B Szabo A +14 more
europepmc +2 more sources
Deep Learning to Differentiate Parkinsonian Syndromes Using Multimodal Magnetic Resonance Imaging: A Proof-of-Concept Study. [PDF]
Abstract Background The differentiation between multiple system atrophy (MSA) and Parkinson's disease (PD) based on clinical diagnostic criteria can be challenging, especially at an early stage. Leveraging deep learning methods and magnetic resonance imaging (MRI) data has shown great potential in aiding automatic diagnosis.
Mattia GM +14 more
europepmc +2 more sources
Structural Alterations Associated With Cardiovascular Autonomic Failure in Multiple System Atrophy. [PDF]
ABSTRACT Background Early severe autonomic failure (AF) in multiple system atrophy (MSA) is a risk factor for poor survival. Postmortem studies suggested that AF is related to the degeneration of preganglionic autonomic neurons of the brainstem and spinal cord. Objectives Characterize cerebral alterations on brain imaging associated with cardiovascular
Georges C +9 more
europepmc +2 more sources
Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20-93: The INSPIRE-T Project. [PDF]
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Lu WH +11 more
europepmc +2 more sources
Disease Progression in Multiple System Atrophy: The ASPIRE Multi-Modal Biomarker Study. [PDF]
Objective The objective of this study was to characterize changes in candidate biomarkers in early multiple system atrophy (MSA) and identify baseline predictors of faster progression. Methods This 1‐year, multicenter, prospective study assessed clinical, neuroimaging (3T‐magnetic resonance imaging [MRI], dopamine transporter single‐photon emission ...
Fabbri M +26 more
europepmc +2 more sources
Trajectories of Pontine Volume in Patients with Multiple System Atrophy. [PDF]
Abstract Objectives To investigate trajectories of regional brain volume changes in multiple system atrophy (MSA) and their potential utility as surrogate markers of disease progression in the cerebellar subtype (MSA‐C). Background Reliable biomarkers for tracking disease progression in MSA are urgently needed.
Kawabata K +19 more
europepmc +2 more sources
Feeling Younger as an Indicator of Better Overall Intrinsic Capacities in the INSPIRE-T Cohort. [PDF]
ABSTRACT Objectives Existing literature indicates that subjective age—the age an individual feels or perceives themselves to be—is associated with various health outcomes. However, its relationship with global indicators such as intrinsic capacity remains inadequately explored.
Cabrol A +8 more
europepmc +2 more sources
Peran Pondok Pesantren Madinatul Ilmi Dalam Pelaksanaan Dakwah Di Desa Kotarindau
Penelitian ini bertujuan untuk mendeskripsikan peran pondok pesantren madinatul ilmi dolo dalam pelaksanaan dakwah di desa kotarindau kecamatan dolo kabupaten sigi melalui kegiatan-kegiatan keagamaan yang melibatkan masyarakat setempat.
Aldiawan
doaj +1 more source
Dinamika psikososial istri sebagai pekerja seks komersial seijin suami
Hidup adalah pilihan, termasuk peran apa yang akan kita pilih dalam mengisi hidup ini, itu sepenuhnya terserah kita. Tetapi terkadang hidup ini kejam, karena seringkali kita dihadapkan kepada pilihan yang semuanya tidak menyenangkan bagi kita.
Asep Guntur Rahayu, Tatie Soeranti
doaj +1 more source
Penelitian ini bertujuan untuk mengkaji perpustakaan yang paling menonjol pada masa Islam klasik berdasarkan sejarah Islam. Islam pada zaman keemasannya pernah menjadi peradaban yang paling maju di dunia. Penelitian berjenis kualitatif deskriptif di mana
Hamidi Ilhami, Moch Isra Hajiri
doaj +1 more source

