Results 61 to 70 of about 255,131 (256)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intention to use AI in accounting education: an analysis from the TAM and TPB perspectives

Frontiers in Education
IntroductionThis study examines the integration of Artificial Intelligence (AI)-based tools into university-level accounting education in Medellín, Colombia.
Diana Yanet Gaviria Rodríguez, Alejandro Valencia-Arias, Juan Guillermo Arango Arango, Juan Manuel Raunelli Sander, Lilian Verde Flores, Jackeline Valencia   +5 more
doaj   +1 more source

The theory of planned behavior as a behavior change model for tobacco control strategies among adolescents in Botswana.

PLoS ONE, 2020
BACKGROUND:Behavioral intentions (motivational factors), attitudes, subjective norm (social pressures), and perceived behavioral control promote or discourage smoking behavior among adolescents.
Roy Tapera, Bontle Mbongwe, Magen Mhaka-Mutepfa, Andrew Lord, Nthabiseng A Phaladze, Nicola M Zetola   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Trust in AI-augmented design: Applying structural equation modeling to AI-augmented design acceptance

Heliyon
With the emergence of Artificial Intelligence (AI) 2.0, computers are now equipped with new creative capabilities and are playing an increasingly significant role in design.
Chuyi Zhou, Xuanhui Liu, Chunyang Yu, Ye Tao, Yanqi Shao   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Academic Cheating with Generative AI in Higher Education: An Extended Model of the Theory of Planned Behavior with Motivational Antecedents

Jurnal Psikologi
This study proposed and tested an extended model of the theory of planned behavior (TPB) to understand the determinants of academic cheating using generative AI (GenAI).
Muhammad Taslim, Riki Purnama Putra, Nurussakinah Daulay, Sefa Bulut   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Job Effort Moderates Associations Between Knowledge Sharing by Chronic Disease Physicians and Patient Health Literacy: Cross-Sectional Study Guided by TPB

Inquiry: The Journal of Health Care Organization, Provision, and Financing
Introduction: Effective knowledge sharing by physicians is integral to patient education and health literacy, particularly in the management of chronic diseases.
Renjie Lu PhD, Shaozhuang Ma PhD, Jing Zhou MA, Jingjie Fan MA, Qiaoxuan Wu PhD   +4 more
doaj   +1 more source