Results 131 to 140 of about 1,944,940 (311)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Determinants of local communities’ intentions to adopt carbon trading: evidence from Tanzania

open access: yesCogent Business & Management
Carbon trading is an emerging economic activity and research area significantly underserved in African countries, particularly Sub-Saharan Africa (SSA). As such, studies examining carbon trading adoption are highly in droughts.
Charles K. Matekele   +2 more
doaj   +1 more source

Perceived Health Benefit and Soy Consumption Behavior: Two Stage Decision Model Approach [PDF]

open access: yes, 2005
A two-stage decision model is developed to assess the effect of perceived soy health benefits on consumers\u27 decisions with respect to soy food. The first stage captures whether or not to consume soy food, while the second stage reflects how often to ...
Balasubramanian, Siva K.   +2 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Relationships Among Perceived Burden, Depressive Cognitions, Resourcefulness, and Quality of Life in Female Relatives of Seriously Mentally Ill Adults [PDF]

open access: yes, 2009
Providing care and support to a seriously mentally ill (SMI) family member can have deleterious effects on one\u27s health and quality of life. This study explored relationships among perceived burden, depressive cognitions, resourcefulness, and quality ...
Bekhet, Abir K.   +2 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERILAKU MEROKOK PADA ATLET BASKET PUTRA UNIVERSITAS X DI KOTA SEMARANG [PDF]

open access: yes, 2016
Dinas Kesehatan Kota Semarang, secara khusus mencatat bahwa 34,4% remaja putra dan 4% remaja putri yang merokok. Angka perilaku merokok yang tinggi pada remaja akhir berasal dari persepsi atau pandangan yang dipercaya tentang merokok itu sendiri.
FEBRINA, INA VIERNISA
core  

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