Results 61 to 70 of about 419,820 (306)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reuse Intentions for Carsharing Services: A Hierarchical Model of Perceived Benefits, Risks, and Individual Differences

Asia Marketing Journal
This study employs a hierarchical component model to examine reuse intentions among experienced carsharing service users in South Korea, focusing on how various perceptions of benefits and risks impact their decisions.
Bo Liu , Sang-Eun Byun, Sookeun Byun
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Perceived benefits of insects as food

, 2023
Insects are presented as an interesting food source in the face of current nutritional and environmental challenges, but pioneering offers are met with much reluctance. This paper investigates the influence of the perceived benefits of entomophagy on attitudes toward insect consumption and, through a comparison between two French and Thai samples ...
openaire   +4 more sources

Revisiting the online shopper's behaviour in Indonesia: The role of trust and perceived benefit

International Journal of Industrial Engineering and Management, 2020
This study attempts to analyze the factors that influence attitudes toward online shopping in Indonesia. The population in this study is consumers who have experience buying products online through social media or e-commerce. The implication of the study
Widyastuti Widyastuti, Sri Hartini, Yessy Artanti   +2 more
doaj   +1 more source

Perceived Benefits of Nature in Diverse Populations

International Journal of Environmental Research and Public Health
The relationship between socioeconomic and demographic characteristics and health effects of green spaces has been studied suggesting that certain groups, such as men, may get more health benefits from nature exposure. However, the link between perceived benefits of nature and socioeconomic and demographic characteristics remains a gap in literature ...
Joy L. Hart, Kandi L. Walker, Cameron K. Stopforth, Anna Simpson, Aruni Bhatnagar, Rachel J. Keith   +5 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Pengaruh Perceived Benefit, Perceived Risk Terhadap Satisfaction Dan Purchase Intention (Study Pada Pengguna Social Commerce Di Instagram) [PDF]

, 2020
Internet memberikan kemudahan bagi para calon pelanggan untuk melakukan pencarian informasi produk. Sebelum melakukan pembelian online, pelanggan mencari informasi untuk meyakinkan dirinya mengenai produk yang akan dibeli.
Novya Astriani
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source