Results 61 to 70 of about 4,041,072 (252)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Residents’ Perceived Benefits as Determinants of Sustainable Tourism Development

open access: yes
This study explores how the benefits residents perceive influence their support for tourism and sustainable practices in nature-based tourism. It highlights the importance of community involvement and local support in achieving sustainable tourism.
Recuero Virto, Nuria   +1 more
core   +1 more source

The Influence of Work-Life Balance Benefits on Family-Supportive Organisational Perception and Work Attitudes [PDF]

open access: yes, 2010
This study investigated the relationship between the availability of, and the use of, work-family balance policies offered by organisations and family-supportive organisational perception (FSOP), work-to-family conflict, continuance and affective ...
Herlin, Paula Kristina
core  

Assessing The Perceived Barriers And Benefits For Milk Products Consumption in Women Living in Tehran

open access: yesآموزش بهداشت و ارتقاء سلامت ایران, 2018
Background and Objective: Dairy product is one of the most important nutrition and has a great role in health. However, it is inadequate intake of this nutrient in Iran. This study aimed to investigate perceived benefits and barriers of dairy consumption
Nahid Kholdi   +5 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Organisational agility and its perceived benefits from Australian perspectives

open access: yes, 2020
Organisational agility helps businesses to sustain their competitive advantage and contributes to business success. It accelerates shared knowledge and learning processes that meet the pace of rapid environmental change.
Mostafa, Sherif
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Urban park soundscapes and their perceived restorativeness [PDF]

open access: yes, 2010
Individual sounds and soundscapes can influence individuals, their place evaluations and potentially their psychological restoration. As urban park soundscapes can vary greatly, ranging from quiet, serene oases to noisy city spaces, it is important to ...
Payne, Sarah R., Payne, Sarah R
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Contextual effects on the perceived health benefits of exercise: The exercise rank hypothesis [PDF]

open access: yes, 2012
Many accounts of social influences on exercise participation describe how people compare their behaviors to those of others. We develop and test a novel hypothesis, the exercise rank hypothesis, of how this comparison can occur.
Taylor, Michael J   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy