Results 51 to 60 of about 116,145 (265)

Perceived Discrimination in LGBTIQ Discourse: A Typology of Verbal Discrimination

PORTAL: Journal of Multidisciplinary International Studies, 2014
New within the field of Discourse Analysis, Perceived Discrimination (PD) is the study of discourse that focuses on the perspective of the victims of discrimination.
Sol Rojas Lizana
doaj   +1 more source

Perceived weight discrimination and risk of incident dementia [PDF]

International Journal of Obesity, 2018
Body mass index (BMI) and obesity have a complex relation with risk of dementia that evolves over the lifespan. Research in other domains indicates that the social experience of body weight, not just BMI, is associated with worse health outcomes. The present research uses data from the Health and Retirement Study (N = 12,053) to test whether weight ...
Sutin, Angelina R., Stephan, Yannick, Robinson, Eric, Daly, Michael, Terracciano, Antonio   +4 more
openaire   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Perceived Neighborhood Crime Safety Moderates the Association Between Racial Discrimination Stress and Chronic Health Conditions Among Hispanic/Latino Adults

Frontiers in Public Health, 2021
Background: Little is known about the link between perceived neighborhood walkability and prevalence of chronic disease. Even less is known regarding this association among Hispanic/Latino adults, despite exhibiting high rates of chronic diseases. Stress
Elizabeth L. Budd, Elizabeth L. Budd, Nicole R. Giuliani, Nicole R. Giuliani, Nichole R. Kelly, Nichole R. Kelly   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Impact of perceived discrimination and coping strategies on well-being and mental health in newly-arrived migrants in Spain.

PLoS ONE, 2023
ObjectivesTo explore how perceived discrimination impacts the emotional well-being and mental health of newly-arrived migrants in Spain; and to identify the coping strategies and behavioral changes used to deal with perceived discrimination.Design102 ...
Aina Gabarrell-Pascuet, Amanda Lloret-Pineda, Marta Franch-Roca, Blanca Mellor-Marsa, Maria Del Carmen Alos-Belenguer, Yuelu He, Rachid El Hafi-Elmokhtari, Felipe Villalobos, Ivet Bayes-Marin, Lola Aparicio Pareja, Oscar Álvarez Bobo, Mercedes Espinal Cabezas, Yolanda Osorio, Josep Maria Haro, Paula Cristóbal-Narvaez   +14 more
doaj   +1 more source

Social Class-Based Discrimination and Psychological Symptoms Among Socioeconomically Disadvantaged College Students: The Moderated Mediation Role of Stress Mindset and Rumination

Frontiers in Psychiatry, 2022
Discrimination as a crucial stressor damages the mental health of socioeconomically disadvantaged individuals through increased ruminative thinking.
Jia Wu, Jia Wu, Qianfeng Li, Qinglu Wu, Qiaoling Li   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source