Results 131 to 140 of about 136,147 (290)

The use of heart rate indices and subjective questionnaires in the determination of fatigue in motor-manual tree felling and delimbing operations in New Zealand exotic plantation forests : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Ergonomics at Massey University [PDF]

, 1996
This study assessed the use of heart rate indices and subjective questionnaires in the determination of fatigue in motor-manual tree felling operations in New Zealand exotic plantation forests. The research design consisted of a causal study utilising an
Kirk, Patrick Michael
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Exploring the Psychological Effects and Physical Exertion of Using Different Movement Interactions in Casual Exergames That Promote Active Microbreaks: Quasi-Experimental Study

JMIR Serious Games
BackgroundProlonged sedentary behavior, such as sitting or reclining, has consistently been identified as a stand-alone risk factor for heightened cardiometabolic risk and overall mortality.
Aseel Berglund, Helena Orädd
doaj   +1 more source

Influence of Moderate Training on Gait and Work Capacity in Fibromyalgia Patients: A Preliminary Field Study [PDF]

, 2002
This field study examined the influence of moderate intensity training on gait patterns and work capacity of individauls with fibromyalgia syndrome (FS).
Dawson, Kimberley A., Pierrynowski, Michael, Tiidus, Peter   +2 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Associations between cognitive–personality traits and perceptual responses during low-volume high-intensity interval exercise in overweight-to-obese adults

Frontiers in Psychology
BackgroundLow-volume high-intensity interval exercise (Lv-HIIE) has been proposed as a time-efficient, effective training approach for adults with overweight or obesity.
Ruohan Zhang, Jingyuan Sun, Jinfa Gu
doaj   +1 more source

133DEPRESSIVE SYMPTOMS ARE ASSOCIATED WITH PERCEIVED, NOT OBJECTIVE, EXERTION DURING EXERCISE IN EUROPEAN, INDIAN ASIAN AND AFRICAN-CARIBBEAN GROUPS [PDF]

, 2019
Sarah‐Naomi James, Siana Jones, Therese Tillin, Daniel Key, Alun D. Hughes, Marcus Richards, Nish Chaturvedi   +6 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Playing tennis matches on clay court surfaces are associated with more perceived enjoyment response but less perceived exertion compared to hard courts [PDF]

, 2018
Bülent Kilit, Erşan Arslan
openalex   +1 more source