Results 151 to 160 of about 1,669,316 (384)

Exploring the Psychological Effects and Physical Exertion of Using Different Movement Interactions in Casual Exergames That Promote Active Microbreaks: Quasi-Experimental Study

JMIR Serious Games
BackgroundProlonged sedentary behavior, such as sitting or reclining, has consistently been identified as a stand-alone risk factor for heightened cardiometabolic risk and overall mortality.
Aseel Berglund, Helena Orädd
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Influence of Moderate Training on Gait and Work Capacity in Fibromyalgia Patients: A Preliminary Field Study [PDF]

, 2002
This field study examined the influence of moderate intensity training on gait patterns and work capacity of individauls with fibromyalgia syndrome (FS).
Dawson, Kimberley A., Pierrynowski, Michael, Tiidus, Peter   +2 more
core   +2 more sources

Associations between cognitive–personality traits and perceptual responses during low-volume high-intensity interval exercise in overweight-to-obese adults

Frontiers in Psychology
BackgroundLow-volume high-intensity interval exercise (Lv-HIIE) has been proposed as a time-efficient, effective training approach for adults with overweight or obesity.
Ruohan Zhang, Jingyuan Sun, Jinfa Gu
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comparison of the perceived subjective exertion and total load lifted response in resistance exercises performed on stable and unstable platforms

Revista Brasileira de Cineantropometria e Desempenho Humano, 2015
This study aimed to compare the perceived subjective exertion (PSE) and total load lifted in resistance exercises performed on stable platforms (SP) and unstable platforms (UP).
Liliane Cunha Aranda, Marcelly Mancini, Yuri Almeida Costa Campos, Elder Dutra Sousa, Jeferson Macedo Vianna, Marzo Edir Da Silva-Grigoletto   +5 more
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Data for "The effects of beet-root juice supplementation on exercise economy, rating of perceived exertion and running mechanics in elite distance runners"

, 2018
Carlos Balsalobre‐Fernández
openalex   +1 more source

The influence of core affect on cyclo-ergometer endurance performance: Effects on performance outcomes and perceived exertion

, 2020
Selenia di Fronso, Antonio Aquino, Réka Zsanett Bondár, Cristina Montesano, Claudio Robazza, Maurizio Bertollo   +5 more
openalex   +1 more source

Smartwatch-Derived Data and Machine Learning Algorithms Estimate Classes of Ratings of Perceived Exertion in Runners: A Pilot Study [PDF]

, 2020
Padraig Davidson, Peter Düking, Christoph Zinner, Billy Sperlich, Andreas Hotho   +4 more
openalex   +1 more source