Results 161 to 170 of about 2,597,074 (300)

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

An holistic evaluation of the workplace: understanding the impact of the workplace environment on satisfaction, perceived productivity and stimulation [PDF]

The central argument in this thesis is that the workplace environment has an impact upon users and that perceptions of the environment are related to overall satisfaction with the workplace, stimulation and perceived productivity.
Thomas, Jenny
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Boxplots of perceived productivity, mood, and stress across stress appraisal states.

Boxplots of perceived productivity, mood, and stress across stress appraisal states.
Mohamad Awada (17720450), Burcin Becerik Gerber (17720453), Gale M. Lucas (6332255), Shawn C. Roll (15856243)   +3 more
core   +1 more source

Side‐Chain Asymmetry in Quinoxaline Copolymer Donors Enables Optimal Morphology and Improved Charge Dynamics for High‐Efficiency Organic Solar Cells

Advanced Science, EarlyView.
Side‐chain asymmetry in quinoxaline copolymer donors modulates donor–acceptor miscibility and blend morphology in all‐polymer solar cells. The asymmetric donor PBAQ6 enables more balanced charge transport, reduced recombination, and improved charge dynamics with PYF‐T‐o, delivering PCEs of 18.35% in binary devices and 19.52% in ternary devices ...
Can Zhu, Jinyuan Zhang, Ke Hu, Shirong Lu, Jianqi Zhang, Shucheng Qin, Hong Zhang, Yule Cheng, Wenbin Lai, Beibei Qiu, Jing Guo, Lei Meng, Gang Li, Yongfang Li   +13 more
wiley   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Understanding the effects of timber rich workplaces on occupants perceived productivity and health: a pilot study. [PDF]

Sci Rep
Whyte S, Skillington K, Candido C, Zhang Y, Fatourehchi D, Finlay S, Chan HF, Kaburagi R, McDonnell KJ, Viana MR, Sarnyai Z.   +10 more
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Report on government services 2016 volume A: approach to performance reporting

, 2016
The annual Report on Government Services (RoGS) provides information on the equity, effectiveness and efficiency of government services in Australia. This report was progressively released between 27 January and 4 February 2016.
Productivity Commission
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Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Increasing Australia's future prosperity - discussion paper

, 2016
This paper was released on 7 November 2016 to assist participants in preparing a submission to the inquiry into Australia’s productivity performance. It outlines a range of issues about which the Commission is seeking information. This paper outlines:
Productivity Commission
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