Results 151 to 160 of about 659,643 (306)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Measuring perceived social support in stroke survivors: Linguistic validation of the Multidimensional Scale of Perceived Social Support (MSPSS) in Hausa (Nigerial) Language

open access: yesSouth African Journal of Occupational Therapy, 2013
Background and Aims: In stroke survivors, social support is believed to affect the quality of patient care and the disease outcome, as well as patients’ physical and psychosocial well-being.
Ashiru Mohammad Hamza   +2 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Mediating effects of social support and socioeconomic status on the association between childhood interpersonal adversity and adulthood mental health in Japan [PDF]

open access: yes
In this study, we examined how the impact of child adversity on adulthood mental health is mediated by perceived social support and socioeconomic status (SES) in Japan, using micro data collected from surveys conducted in four municipalities in the Tokyo
Umeda, Maki   +2 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Exploring the role of country-level gender equality in the link between relationship status and perceived social support across 49 countries

open access: yesScientific Reports
Past studies have demonstrated that higher perceived social support among coupled individuals and greater gender equality foster a more supportive social context.
Agnieszka E. Łyś, Katarzyna Adamczyk
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Bridging the islands of society : modeling delinquency prevention through optimization of social support

open access: yes, 2011
The purpose of the meta-analysis is to present a theoretical model of social work interventions within the process of juvenile delinquency prevention. The study approaches delinquency prevention as the process of increasing the amount of social support ...
Rimkus, Valdas
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

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