Results 191 to 200 of about 569,650 (292)

The relationship between digital literacy, perceived usefulness, and learning satisfaction among medical students in blended learning: the mediating role of learning engagement. [PDF]

BMC Med Educ
Ai L, Hoon TS, Wang Q, Mohamad SNA.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Perceived satisfaction, perceived usefulness, and interactive learning environments as predictors of university students' self-regulation in the context of GenAI-assisted learning: an empirical study in mainland China. [PDF]

Front Psychol
Liu Z, Zhao Y, Zuo H, Lu Y.
europepmc   +1 more source

Perceived usefulness of, engagement with, and effectiveness of virtual reality environments in learning industrial operations: the moderating role of openness to experience. [PDF]

Virtual Real, 2023
Wong EY, Hui RT, Kong H.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A quasi-randomised pilot study on the efficacy and perceived usefulness of adding chemosignals to mindfulness practice for women with social anxiety. [PDF]

Sci Rep
Eliasson ET, Vigna E, Dal Bò E, Cecchetto C, Zurlo L, Gentili C, Scilingo EP, Greco A, Di Francesco F, Citi L, Vanello N, Lundström JN, Hadlaczky G, Carli V.   +13 more
europepmc   +1 more source

An interview study to explore the perceived usefulness of in-house training programs in tourism and hospitality education. [PDF]

Heliyon, 2022
Fuchs K.
europepmc   +1 more source

Design Thinking and Participation: Lessons Learned from Three Case Studies [PDF]

This paper examines how design thinking and serious games approaches can be used to support participation through the analysis of three case studies. Indeed we will analyze these approaches in three different contexts: (i) a state-owned multi-utilities ...
Giorgio Pauletto, Jean-Henry Morin, Olivier Glassey, Patrick Genoud   +3 more
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Influence of Pre-Service Training on STEM Teachers' Attitudes Toward ICT-Enhanced Teaching: Mediating Roles of Perceived Ease of Use and Perceived Usefulness. [PDF]

Behav Sci (Basel)
Zhang Y, Zhu J.
europepmc   +1 more source