Results 191 to 200 of about 78,689 (266)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Investigation of the impact of cognitive load on EFL learners' satisfaction with MOOCs: the mediating role of expectation confirmation and perceived usefulness. [PDF]

BMC Psychol
Ma L.
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The mediating role of satisfaction in the relationship between perceived usefulness, perceived ease of use and students' behavioural intention to use ChatGPT. [PDF]

Sci Rep
Alshammari SH, Babu E.
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Perceived usefulness of a blended learning approach for skills training among medical interns: a pilot study. [PDF]

BMC Med Educ
Ramachandran R, Kaur R, Roy A, Goel P, Deorari AK.   +4 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Adolescents' use and perceived usefulness of generative AI for schoolwork: exploring their relationships with executive functioning and academic achievement. [PDF]

Front Artif Intell
Klarin J, Hoff E, Larsson A, Daukantaitė D.   +3 more
europepmc   +1 more source

Quality and Perceived Usefulness of Patient-Submitted Store-and-Forward Teledermatology Images.

JAMA Dermatol, 2022
Jiang SW, Flynn MS, Kwock JT, Liu B, Quow K, Blanchard SK, Breglio KF, Fresco A, Jamison MO, Lesesky E, Bellet JS, Green CL, Shearer SM, Nicholas MW.   +13 more
europepmc   +1 more source