Results 91 to 100 of about 5,827,073 (337)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Change Detection in Remote Sensing Images Based on Image Mapping and a Deep Capsule Network

Remote Sensing, 2019
Homogeneous image change detection research has been well developed, and many methods have been proposed. However, change detection between heterogeneous images is challenging since heterogeneous images are in different domains.
Wenping Ma, Yunta Xiong, Yue Wu, Hui Yang, Xiangrong Zhang, Licheng Jiao   +5 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Fully Dense Multiscale Fusion Network for Hyperspectral Image Classification

Remote Sensing, 2019
The convolutional neural network (CNN) can automatically extract hierarchical feature representations from raw data and has recently achieved great success in the classification of hyperspectral images (HSIs).
Zhe Meng, Lingling Li, Licheng Jiao, Zhixi Feng, Xu Tang, Miaomiao Liang   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Double-Branch Multi-Attention Mechanism Network for Hyperspectral Image Classification

Remote Sensing, 2019
Recently, Hyperspectral Image (HSI) classification has gradually been getting attention from more and more researchers. HSI has abundant spectral and spatial information; thus, how to fuse these two types of information is still a problem worth studying.
Wenping Ma, Qifan Yang, Yue Wu, Wei Zhao, Xiangrong Zhang   +4 more
doaj   +1 more source

Scattering of Electromagnetic Wave by system of core/shell microsphere and nanoparticle

Advanced Electromagnetics, 2020
The paper deals with the scattering of an electromagnetic plane wave by a system of core/shell microspheres and a single nanoparticle placed outside the spheres.
A. Abramov, A. Kostikov, Y. Yue
doaj   +1 more source

Concepts in Perception [PDF]

, 1988
I can agree with much of what D.H. Mellor says in his response to my paper ('Crane's Waterfall Illusion'). I can agree that perception in some sense 'aims' at truth, that its function 'is to tell us how the world truly is'..
Crane, Tim
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source