Results 91 to 100 of about 557,205 (269)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Perceptions about brain health among the United Arab Emirates population using the global brain survey: a cross-sectional study

Frontiers in Public Health
IntroductionInterest in brain health and general well-being research has increased due to advances in neurosciences, and aging population’s need for preventive health measures.
Iffat Elbarazi, Aminu S. Abdullahi, Karim Abdel Aziz, Emmanuel Stip, Emmanuel Stip, Ismail Elkonaisi, Fayeza Fahim, Maryum Asghar, Isabelle Budin-Ljøsne, Javaid Nauman, Javaid Nauman, Javaid Nauman   +11 more
doaj   +1 more source

THE UKRAINIAN CRISIS - AN UNPREDICTABLE EVENT? [PDF]

CES Working Papers, 2016
For years Ukraine tried to balance between the EU and Russia. The strategy proved to be inefficient due to the fact that Ukraine did not hold the required leverage for this kind of strategy and the consequence was observed in the current instability from
Ana Maria COSTEA
doaj  

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Fishing to farming livelihood diversification: Perceptions from commercial fishers and shellfish farmers in the United States

People and Nature
Aquaculture, or the farming of aquatic species, is a rapidly growing, multi‐billion‐dollar sector of the U.S. food industry. At the same time, many wild capture fisheries are contending with financial, social or ecological challenges that threaten ...
Hayley R. Lemoine, Adriane K. Michaelis, Sarah E. Lester   +2 more
doaj   +1 more source

Perceptions and preferences of patient services in emergency departments in Jeddah: a comprehensive survey

Saudi Journal of Emergency Medicine
Objective: This study investigated the preferences and perception of the participants regarding patient services in Emergency Department (ED). Methods: A vast comprehensive survey, targeting a sample size of 597 participants in the Jeddah region, was ...
Adeeb Omer Bukhari, Sami Omar Baarimah, Reem Wajdi Ba-Arma, Mayar Adeeb Bukhari   +3 more
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Exploring Radiographers' Readiness for Artificial Intelligence in Kuwait: Insights and Applications

Health Science Reports
Introduction There is a growing adoption of artificial intelligence (AI) in the field of medical imaging. AI can potentially enhance patient care, improve workflow, and analyze patient's medical data. This study aimed to explore radiographers' knowledge,
Asseel Khalaf, Manar Alshammari, Hawraa Zayed, Maryam Emnawer, Abdulmohsen Esfahani   +4 more
doaj   +1 more source