Results 91 to 100 of about 129,019 (321)

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Effect of perchlorate and thiocyanate exposure on thyroid function of pregnant women from South-West England: a cohort study

Thyroid Research, 2018
BackgroundIodine is important for thyroid hormone synthesis, and iodine deficiency in pregnancy may impair fetal neurological development. As perchlorate and thiocyanate inhibit sodium-iodide symporter reducing the transport of iodine from circulation ...
B. Knight, B. Shields, Xuemei He, E. Pearce, L. Braverman, R. Sturley, B. Vaidya   +6 more
semanticscholar   +1 more source

Microscopic observations of X-ray and gamma-ray induced decomposition of ammonium perchlorate crystals [PDF]

, 1972
The X-ray and gamma-ray induced decomposition of ammonium perchlorate was studied by optical, transmission, and scanning electron microscopy. This material is a commonly used oxidizer in solid propellents which could be employed in deep-space probes, and
Herley, P. J., Levy, P. W.
core   +1 more source

Surface Engineered Biomolecular Condensates for Targeted Cell Cytotoxicity

Advanced Science, EarlyView.
Interfacial engineering of biomolecular condensates with a decanoic acid (DA) membrane enables molecular‐weight‐gated enzyme localization. Small biomolecules (≤60 kDa) enrich internally, while high‐molecular‐weight alkaline phosphatase (ALP) localizes at the interface.
Chengying Yin, Cheng Wu, Xinran Yu, Yifeng Zhu, Baohu Wu, Yue Wang, Liangfei Tian   +6 more
wiley   +1 more source

Sources and pathways of human exposure to perchlorate in the United States: A comparison of environmental monitoring and biomonitoring approaches

Environmental Chemistry and Ecotoxicology
Perchlorate is a widespread environmental pollutant and a known thyroid hormone disruptor. Little is known about the sources and pathways of human exposure to perchlorate.
Kurunthachalam Kannan, Qian Wu, Zhong-Min Li   +2 more
doaj   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

Electron Photodetachment from Aqueous Anions. I. Quantum Yields for Generation of Hydrated Electron by 193 and 248 nm Laser Photoexcitation of Miscellaneous Inorganic Anions

, 2004
Time resolved transient absorption spectroscopy has been used to determine quantum yields for electron photodetachment in 193 nm and (where possible) 248 nm laser excitation of miscellaneous aqueous anions, including hexacyanoferrate(II), sulfate ...
Crowell, R. A., Sauer, Myran C., Shkrob, Ilya A.   +2 more
core   +1 more source

Bioorthogonal Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation

Advanced Science, EarlyView.
Bioorthogonal SDPTAC harnesses US‐responsive Ce6‐TCO and Tz ligands via IEDDA click chemistry to assemble degraders in situ, generating ROS that selectively eliminate nuclear, cytosolic, and membrane proteins, thereby suppressing deep‐seated tumors in vivo.
Yuhan Bao, Yaojin Zhu, Xinhao Wei, Yuxin Fang, Jiayi Zhu, Fei Gao, Guoqiang Dong, Shipeng He, Chunquan Sheng   +8 more
wiley   +1 more source

RETROSPECTIVE ANALYSIS OF DYSHORMONGENETIC GOITRE [PDF]

, 2012
Dyshormonogenetic goitre is a rare thyroid entity which occurs due to enzymatic deficiency in the physiological process of thyroxin synthesis resulting in goitre formation. This has to be differentiated from iodine deficiency goitres for their similarity
Maharajan, Chandrasekaran, Vedachalam, Sucharitha   +1 more
core   +1 more source

Synthesis of racemic and chiral BEDT-TTF derivatives possessing hydroxy groups and their achiral and chiral charge transfer complexes [PDF]

, 2015
Chiral molecular crystals built up by chiral molecules without inversion centers have attracted much interest owing to their versatile functionalities related to optical, magnetic, and electrical properties.
Hashimoto, C, Krivickas, SJ, Mori, H, Takahashi, K, Ueda, A, Wallis, JD, Yoshida, J   +6 more
core   +3 more sources