Results 151 to 160 of about 1,363 (228)

A Synergistic Dual‐Antibody Cocktail Targeting α‐Toxin Protects Against Invasive Staphylococcus aureus Infection by Neutralizing Virulence and Enhancing Host Defense

MedComm, Volume 7, Issue 7, July 2026.
Two Hla‐targeting monoclonal antibodies (Hm0399, Hm0411) were isolated from rFSAV‐vaccinated volunteers. Their cocktail (Hm3‐4) showed synergistic anti‐S. aureus activity. Hm0411 blocks Hla‐receptor binding via salt bridges; Hm0399 potentiates Fc effector functions through hydrogen bonds.
Liqun Zhao, Zhen Song, Hongyin Fan, Lei Wang, Yun Yang, Haiming Jing, Xin Xia, Yu Wang, Leilei Feng, Sheng Wang, Zhifu Chen, Qiang Gou, Yue Yuan, Jinyong Zhang, Quanming Zou, Hao Zeng   +15 more
wiley   +1 more source

Perchlorate in stratospheric aerosol particles. [PDF]

Proc Natl Acad Sci U S A
Murphy DM, Abou-Ghanem M, Ahern AT, Brock CA, Cziczo DJ, Hintsa EJ, Jacquot JL, Lawler MJ, Lyu M, Moore FL, Robinson MA, Roberts JM, Schill GP, Shen X, Thornberry TD, Veres PR.   +15 more
europepmc   +1 more source

From atoms to a data bank: optimizing transferability of electron‐density symmetry

Acta Crystallographica Section A, Volume 82, Issue 4, Page 256-275, July 2026.
This work focuses on the electron density of atoms modeled with a multipolar approach. We investigate how the refinement of the multipole models with/without symmetry constraints and optimization of the orientation of the local coordinate system and pseudosymmetry assignment improves the accuracy of electron‐density representations for atoms and atom ...
Paulina Maria Rybicka, Marta Kulik, Vladislav Ignat'ev, Paulina Maria Dominiak   +3 more
wiley   +1 more source

Synthetic biology for space exploration. [PDF]

NPJ Microgravity
Onofri S, Moeller R, Billi D, Balsamo M, Becker A, Benvenuto E, Cassaro A, Catanzaro I, Cockell CS, Desiderio A, Ellis T, Gonzáles-Pastor JE, Hahn C, Leys N, Leo P, Maurel MC, Pacelli C, Pavletic B, Ripa C, Rothschild LJ, Surdo L.   +20 more
europepmc   +1 more source

Principles of Food Safety and Toxicological Risk Assessment: Refining Hazards, Risk Management Communication, and Common Misconceptions

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Toxicology has evolved into a robust scientific discipline since the 16th century when Paracelsus, the “Father of Toxicology,” established the basic yet fundamental principle that “the dose makes the poison.” Toxicology is often first associated with the chemical and pharmaceutical industries; however, it plays an equally relevant role in ...
Kenneth S. Rivera‐González, Jay S. Petrick, Christine M. Crincoli, Matthew D. Teegarden, Paul R. Hanlon   +4 more
wiley   +1 more source

Rational Design of Crown Ether‐Based Fluorescent Sensors for Group II Cations: Insights From Vibrational Spectroscopy and Computation

ChemPhysChem, Volume 27, Issue 12, 26 June 2026.
We use vibrational spectroscopy to determine the solution phase structures of complexes of two fluorescent sensors with metal ions. We use these to understand differences in the absorption spectra and to explain why even very low levels of water destroy the fluorescent response. Rational design of fluorescent sensors requires knowledge of the molecular
Bruno Martinez‐Haya, Jennifer C. Anene, Laura Finazzi, Jos Oomens, Simon Wheeler   +4 more
wiley   +1 more source

The elusive nature of Martian liquid brines. [PDF]

Proc Natl Acad Sci U S A
Chevrier VF, Slank RA.
europepmc   +1 more source

Morphological Control of Aurophilic Chains of Gold(I) Dithiolate Dimers With Alkali and Alkali Earth Cations

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Luminescent coordination polymers of Group 1 (Li, K, Cs) and 2 (Mg─Ba) cations with gold(I) iso‐maleonitriledithiolate ({Au2[S2C = C(CN)2]}2−) units were prepared; 1‐D aurophilic chains are present in all cases. The structures strongly depend on cation charge and size, with N‐cyano coordination observed in the Gp 1 and larger Gp 2 cations. Increasingly
Jefferson A. Pells, William W. L. Ho, Daniel B. Leznoff   +2 more
wiley   +1 more source

Salt Formation of the Alliance of Triazole and Oxadiazole Towards Balanced Energy and Safety. [PDF]

Materials (Basel)
Liu Y, Wang M, Men J, Li B, Feng S, Zhu S, Liu G, Gou R, Zhang S, Lu M, Yang L.   +10 more
europepmc   +1 more source

Lunar and Martian Regolith Simulants Desorb and Weather after Exposure to Bioregenerative Life Support System Effluent. [PDF]

ACS Earth Space Chem
Coker HR, Saetta D, Tessema MM, Smith JL, Richardson-Gongora CA, Fischer JA, Roberts HI, Roberson LB, Howe JA.   +8 more
europepmc   +1 more source