Results 81 to 90 of about 23,603 (268)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
PLoS ONENumerous centrality measures exist to quantify the influence of edges within a network, with edge betweenness being one of the more well-known measures.
Christina Durón +2 more
doaj +1 more source
Banach Center Publications, 2018 One of the most well known random fractals is the so-called Fractal percolation set. This is defined as follows: we divide the unique cube in $\mathbb{R}^d$ into $M^d$ congruent sub-cubes. For each of these cubes a certain retention probability is assigned with which we retain the cube.
Simon, Károly, Vágó, Lajos
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Thermal Conductivity of Suspension of Aggregating Nanometric Rods
Entropy, 2016 Enhancing thermal conductivity of simple fluids is of major interest in numerous applicative systems. One possibility of enhancing thermal properties consists of dispersing small conductive particles inside. However, in general, aggregation effects occur
Amine Ammar +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
An advance in infinite graph models for the analysis of transportation networks
International Journal of Applied Mathematics and Computer Science, 2016 This paper extends to infinite graphs the most general extremal issues, which are problems of determining the maximum number of edges of a graph not containing a given subgraph.
Cera Martín, Fedriani Eugenio M.
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Frontiers in Earth Science, 2018 Core formation has left a lasting geochemical signature on the Earth. In order to constrain the composition of the Earth we must fully understand the processes by which newly formed Earth, and the bodies which accreted to it, differentiated.
Madeleine T. L. Berg +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source