Results 121 to 130 of about 437,318 (266)

Brachiocephalic trunk damage resulted from percutaneous tracheotomy

, 2016
The paper presents a rare case of injury to the brachiocephalic trunk wall during percutaneous tracheotomy. The complication developed in a post-cardiac arrest patient in a poor general condition.
Małgorzata Brzozowska, Magdalena Kwiatkowska, Mieszko Olczak, Sylwia Tarka   +3 more
core   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Combined MitraClip and TriClip therapy in patients with severe mitral and tricuspid regurgitation: determinants and prediction of mid-term outcomes

Frontiers in Cardiovascular Medicine
BackgroundPatients with combined severe mitral (MR) and tricuspid regurgitation (TR) constitute a high-risk cohort with advanced right-heart disease, reduced survival, and frequent heart failure hospitalizations.
Giuseppe D´Ancona, Giuseppe D´Ancona, Mohamed Al Saidi, Mohamed Al Saidi, Antonia Ourani, Antonia Ourani, Jörg Hering, Jörg Hering, Robert Gramlich, Robert Gramlich, Sebastian Feickert, Sebastian Feickert, Kristof Biernath, Kristof Biernath, Plamen Kochev, Plamen Kochev, Jonas Michael Bodanowitz, Jonas Michael Bodanowitz, Hüseyin Ince, Hüseyin Ince   +19 more
doaj   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Percutaneous cementoplasty for painful osteolytic distal femur metastases: a case report

, 2016
Mingxing Lei,1 Yaosheng Liu,1 Shaoxing Yang,2 Weigang Jiang,1 Yuncen Cao,1 Shubin Liu1 1Department of Orthopedic Surgery, 2Department of Pulmonary Neoplasms Internal Medicine, The Affiliated Hospital of Academy of Military Medical Sciences, Beijing ...
Liu Y, Lei M, Jiang W, Cao Y, Liu S, Yang S   +5 more
core  

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Coronary artery compression in percutaneous pulmonary valve implantation: a case series

Frontiers in Cardiovascular Medicine
Catastrophic complications of coronary artery compression after percutaneous pulmonary valve implantation (PPVI) are uncommon in patients with a dysfunctional native right ventricular outflow tract after Tetralogy of Fallot repair (rTOF). Nonetheless, we
Rujira Buntharikpornpun, Supaporn Roymanee, Worakan Promphan, Phuoc Duong   +3 more
doaj   +1 more source

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang, Nailin Yang, Shuangshuang Ji, Siping Meng, Di Wang, Wenjun Liang, Xuming Bai, Yong Jin, Xingwei Sun   +8 more
wiley   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source