Results 161 to 170 of about 692,181 (344)

Nanozyme‐Engineered Probiotic Microneedle Patch for Chronic Diabetic Wound Therapy

open access: yesAdvanced Science, EarlyView.
This work introduces a robust living‐materials‐based strategy that integrates microbial therapy with catalytic nanotechnology for effective management of chronic infected wounds via alleviating reactive oxygen species (ROS), combating bacterial infection, relieving hypoxia, and exerting anti‐inflammatory effects.
Xueyang Wang   +7 more
wiley   +1 more source

COMBINED PERCUTANEOUS RETROGRADE AORTIC AND TRANSSEPTAL LEFT HEART CATHETERIZATION [PDF]

open access: bronze, 1964
G. B. Peckham   +3 more
openalex   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

open access: yesAdvanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang   +28 more
wiley   +1 more source

Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

open access: yesAdvanced Science, EarlyView.
This study develops self‐assembled Dictamni Cortex (BXP)‐Fe(III) infinite coordination polymer nanoparticles (NB) to improve BXP's solubility and bioavailability for psoriasis. NB transdermally treats psoriasis by targeting the epigenetic regulator CTCF (CCCTC‐binding factor), suppressing HSP90AB1 (heat shock protein 90 alpha family class B member 1 ...
Zhengyi Zhang   +15 more
wiley   +1 more source

Microneedle‐Based Biofuel Cell with MXene/CNT Hybrid Bioanode: Fundamental and Biomedical Application

open access: yesAdvanced Science, EarlyView.
A hybrid microneedle‐based biofuel cell composed of MXene/CNT/glucose oxidase bioanode and platinum/carbon cathode was prepared for wearable transdermal charged drug delivery system. It harvests the subcutaneous interstitial fluid energy and exhibits a stable transdermal current of 4‐6 µA@5 kΩ.
Shoujie Guan   +8 more
wiley   +1 more source

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

open access: yesAdvanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

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